多肽定制ω-Conotoxin GVIA|omega-ConoGVIAn GVIA 编码 [106375-28-4]

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名称 ω-Conotoxin GVIA|omega-ConoGVIAn GVIA
编码 [106375-28-4]
别名 ω-Conotoxin GVIA|omega-ConoGVIAn GVIA
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) CKS(Hyp)GSSCS(Hyp)TSYNCCRSCN(Hyp)YTKRCY-NH2(Disulfide bridges: Cys1-Cys16, Cys8-Cys19, Cys15-Cys26)
序列(三字母缩写) H-Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2?(trifluoroacetate salt)(Disulfide bridges: Cys1-Cys16, Cys8-Cys19, Cys15-Cys26)
基本描述 Reversible N-type Ca2+ Channel Blocker W-Conotoxin MVIIA, originally isolated from the venom of the fish-hunting cone snail Conus magus, is a blocker of voltage-sensitve Ca2+ channels in neurons. It has been used to identify different Ca2+ channel subtypes in amphibian brain.
溶解度
分子量 3037.39
化学式 C120H182N38O43S6
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents ω-Conotoxin GVIA|omega-ConoGVIAn GVIA          编码     [106375-28-4]
Figures ω-Conotoxin GVIA|omega-ConoGVIAn GVIA          编码     [106375-28-4]
Reference Rivier, J. et al. J. Biol. Chem. 262, 1194 (1987) Lampe, RA. et al. Biochem. 32, 3255 (1993) Wright, C. and JA. Angus, J. Cardiovasc. Pharmacol. 30, 392 (1997) Serone, A. and JA. Angus, Br. J. Pharmacol. 127, 927 (1999). B.M. Olivera, J.M. Mclntosh, L.J. Cruz, F.A. Luque, and W.R. Gray, Biochemistry, 23, 5087 (1984). (Original) Y. Nishiuchi, K. Kumagaye, Y. Noda, T.X. Watanabe, and S. Sakakibara, Biopolymers, 25, S61 (1986). (Chem. Synthesis and S-S Bond) B.M.Olivera et al., Biochemistry, 23, 5087 (1984) B.M.Olivera et al., Biochemistry, 26, 2086 (1987) J.Rivier et al., J. Biol. Chem., 262, 1194 (1987) D.R.Hillyard et al., Neuron, 9, 69 (1992) K.Sato et al., Biochem. Biophys. Res. Commun., 194, 1292 (1993) J.R.Abbott and M.J.Litzinger, Int. J. Devl Neurosci., 12, 43 (1994)
C端
N端
化学桥 (Disulfide bridges: Cys1-Cys16, Cys8-Cys19, Cys15-Cys26)

多肽定制ω-Conotoxin MVIIA|omega-Conotoxin MVIIA 编码 [107452-89-1]

上海金畔生物科技有限公司可以定制不同序列多肽,可以访问官网了解更多产品信息。

名称 ω-Conotoxin MVIIA|omega-Conotoxin MVIIA
编码 [107452-89-1]
别名 ω-Conotoxin MVIIA|omega-Conotoxin MVIIA
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) CKGKGAKCSRLMYDCCTGSCRSGKC-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and CYs15-Cys25)
序列(三字母缩写) H-Cys-Lys-Gly-Lys-Gly-Ala-Lys-Cys-Ser-Arg-Leu-Met-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Ser-Gly-Lys-Cys-NH2 (trifluoroacetate salt)(Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and CYs15-Cys25)
基本描述 Hypothalamic hormone that stimulates the synthesis and release of ACTH from the anterior pituitary.
溶解度
分子量 2639.1
化学式 C102H172N36O32S7
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents ω-Conotoxin MVIIA|omega-Conotoxin MVIIA          编码     [107452-89-1]
Figures ω-Conotoxin MVIIA|omega-Conotoxin MVIIA          编码     [107452-89-1]
Reference Olivera, BM. et al. Biochem. 26, 2086 (1987) Hillyard, DR. et al. Neuron. 9, 69 (1992). B.M. Olivera, L.J. Cruz, V. de Santos, G.W. Le Cheminant, D. Griffin, R. Zeikus, J.M. McIntosh, R. Galyean, J. Varga, W.R. Gray, and J. Rivier, Biochemistry, 26, 2086 (1987). (Original) K. Valentino, R. Newcomb, T. Gadbois, T. Singh, S. Bowersox, S. Binter, A. Justice, D. Yamashiro, B.B. Hoffman, R. Ciaranello, G. Miljanich, and J. Ramachandran, Proc. Natl. Acad. Sci. USA, 90, 7894 (1993). (Pharmacol.) J.A. Fox, Pflügers Arch., 429, 873 (1995). (Pharmacol.)
C端
N端
化学桥 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and CYs15-Cys25)

多肽定制ω-Conotoxin MVIIC|omega-Conotoxin MVIIC 编码 [147794-23-8]

上海金畔生物科技有限公司可以定制不同序列多肽,可以访问官网了解更多产品信息。

名称 ω-Conotoxin MVIIC|omega-Conotoxin MVIIC
编码 [147794-23-8]
别名 ω-Conotoxin MVIIC|omega-Conotoxin MVIIC
纯度 80%,90%,95%,98%,99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列(单字母缩写) CKGKGAPCRKTMYDCCSGSCGRRGKC-NH2 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and Cys15-Cys26)
序列(三字母缩写) H-Cys-Lys-Gly-Lys-Gly-Ala-Pro-Cys-Arg-Lys-Thr-Met-Tyr-Asp-Cys-Cys-Ser-Gly-Ser-Cys-Gly-Arg-Arg-Gly-Lys-Cys-NH2 (trifluoroacetate salt)(Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and Cys15-Cys26)
基本描述 Gastrointestinal hormone and a member of the endothelin family that exerts a direct effect on the pituitary and increases pulmonary arterial pressure. This peptide also displays a higher contractor activity on mouse and guinea pig, whereas it is weaker in its vasoconstrictor activity.
溶解度
分子量 2749.3
化学式 C106H178N40O32S7
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents ω-Conotoxin MVIIC|omega-Conotoxin MVIIC          编码     [147794-23-8]
Figures ω-Conotoxin MVIIC|omega-Conotoxin MVIIC          编码     [147794-23-8]
Reference McDonough, S. et al. J. Neurosci. 16, 2612 (1996) Hillyard, DR. et al. Neuron. 9, 69, (1992)
C端
N端
化学桥 (Disulfide bridge: Cys1-Cys16, Cys8-Cys20, and Cys15-Cys26)