2-甲氧基抗霉素A3

储存在-20℃。存放在干燥的条件下。该产品最多可存储12个月。

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

2-甲氧基抗霉素A3

2-甲氧基抗霉素A3通过抑制Bcl-xL和Bcl-2诱导线粒体膜电位去极化来诱导癌细胞凋亡。减少肿瘤大小而无明显的细胞毒性。

Potent mGluR ligand with similar selectivity and potency to glutamate but without ionotropic activity. Conformationally restricted ACPD analog. Neuroprotective.

抗霉素A1

抗霉素A1是一种疏水性抗霉素A复合物，在一系列生物测定中均显示出强大的抗真菌，驱虫，杀虫，抗病毒和抗肿瘤活性。抗霉素A1通过抑制HIF-1a激活引起的VEGF产生的减少来抑制血管生成。

Antimycin A1 is a hydrophobic antimycin A complex which exhibits potent antifungal, anthelmintic, insecticidal, antiviral and antitumor activity across a range of bioassays. Antimycin A1 inhibits angiogenesis via a decrease in VEGF production caused by inhibition of HIF-1a activation.

抗霉素A2

抗霉素A2是抗霉素复合物的同系物，最早于1959年从抗霉素A1中分离出来。抗霉素A2与所有抗霉素一样，是一种有效的呼吸抑制剂，通过抑制泛醇氧化为泛醌的作用。抗霉素A2具有广泛的生物学活性，具有抗真菌，驱虫，杀虫，抗病毒和抗肿瘤活性。缺乏单独的抗霉素成分阻碍了人们对抗霉素复合物成分的共同和独特分子靶标的更多理解。

Antimycin A2 is a homologue of the antimycin complex, first resolved from antimycin A1 in 1959. Antimycin A2, like all antimycins, is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A2 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active. Lack of availability of the individual antimycin components has hindered greater understanding of the common and unique molecular targets of the components of the antimycin complex.

抗霉素A3

抗霉素A3是抗霉素复合物的同系物。抗霉素A3是A1和A2的极性更强的类似物，并且是通过抑制泛醇氧化为泛醌的有效呼吸抑制剂。抗霉素A3具有广泛的生物学活性，具有抗真菌，驱虫，杀虫，抗病毒和抗肿瘤活性。

产品介绍：

Antimycin A3 是从多种链霉菌中分离出来的抗生素，具有抗真菌活性。Antimycin A3 是有效的呼吸 (respiration) 抑制剂。Antimycin A3 抑制泛醇-细胞色素 c 氧化还原酶 (ubiquinol-cytochrome c oxidoreductase) 的电子转移活性，并阻止人类癌细胞的生长。Antimycin A3 也抑制 ATP 柠檬酸裂解酶，Ki 值为 60.1 µM。

Antimycin A3 is a homologue of the antimycin complex. Antimycin A3 is a more polar analogue of A1 and A2 and is a potent inhibitor of respiration by inhibiting the oxidation of ubiquinol to ubiquinone. Antimycin A3 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active.

抗霉素A4

抗霉素A4是抗霉素复合物的主要成分中极性最强的一种，也是一种有效的呼吸抑制剂。抗霉素A4具有广泛的生物学活性，具有抗真菌，驱虫，杀虫，抗病毒和抗肿瘤活性。

Antimycin A4 is the most polar of the major components of the antimycin complex and a potent inhibitor of respiration. Antimycin A4 exhibits broad biological activity as an antifungal, anthelmintic, insecticidal, antiviral and antitumor active.