桑辛素对照品

发表于2024年2月29日由上海金畔生物科技有限公司

桑辛素对照品

【编号】：PR0961

【产品名称】：桑辛素对照品

【规格】：10mg

【用途】：

　　桑辛素对照品

　　编号：PR0961

　　英文名称：Morusin

　　英文别名: Mulberrochromene

　　Cas 号: 62596-29-6

　　分子式：C25H24O6

　　分子量：420.461

　　植物来源：桑白皮

　　来源: the root bark of Morus alba (mulberry) and other Morus spp.

　　纯度: 95%~99%

　　分析方法: HPLC-DAD or/and HPLC-ELSD

　　鉴定方法: 质谱（Mass）, 核磁（NMR）

　　包装: 棕色小玻璃瓶，标准包装10mg，20mg，50mg；可以按客户需求包装。

　　类别：上海金畔生物科技有限公司，天然提取物

　　作为标准品，对照品或者供研究用，不能直接用于人体。

Moracin P(Synonyms: 桑辛素P)

发表于2024年1月4日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Moracin P (Synonyms: 桑辛素P)

Moracin P 是从 Mori Cortex Radicis 中分离出来的 2-芳基苯并呋喃。Moracin P 对缺氧诱导因子 (HIF-1) 表现出强大的体外抑制活性。Moracin P 减少了氧葡萄糖剥夺 (OGD) 诱导的活性氧 (ROS) 的产生。Moracin P 具有神经保护和抗炎作用。

Moracin P Chemical Structure

CAS No. : 102841-46-3

规格		是否有货
5 mg		询价
10 mg		询价
25 mg		询价

* Please select Quantity before adding items.

生物活性	Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects^[1]^[2]^[3].
体外研究 (In Vitro)	Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC₅₀ value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC₅₀ values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	326.34
Formula	C₁₉H₁₈O₅
CAS 号	102841-46-3
中文名称	桑辛素P
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Moracin O(Synonyms: 桑辛素O)

发表于2024年1月4日由上海金畔生物科技有限公司

Moracin O (Synonyms: 桑辛素O)

Moracin O 是从 Mori Cortex Radicis 中分离出来的 2-芳基苯并呋喃。Moracin O 对缺氧诱导因子 (HIF-1) 表现出强大的体外抑制活性。Moracin O 减少了氧葡萄糖剥夺 (OGD) 诱导的活性氧 (ROS) 的产生。Moracin O 具有神经保护和抗炎作用。

Moracin O Chemical Structure

CAS No. : 123702-97-6

规格	价格	是否有货
5 mg	￥3700	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	Moracin O is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects^[1]^[2]^[3].
体外研究 (In Vitro)	Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC₅₀ value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC₅₀ value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	326.34
Formula	C₁₉H₁₈O₅
CAS 号	123702-97-6
中文名称	桑辛素O
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Moracin P(Synonyms: 桑辛素P)

发表于2024年1月4日由上海金畔生物科技有限公司

Moracin P (Synonyms: 桑辛素P)

Moracin P Chemical Structure

CAS No. : 102841-46-3

规格		是否有货
5 mg		询价
10 mg		询价
25 mg		询价

* Please select Quantity before adding items.

生物活性	Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects^[1]^[2]^[3].
体外研究 (In Vitro)	Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC₅₀ value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC₅₀ values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	326.34
Formula	C₁₉H₁₈O₅
CAS 号	102841-46-3
中文名称	桑辛素P
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Moracin P(Synonyms: 桑辛素P)

发表于2024年1月4日由上海金畔生物科技有限公司

Moracin P (Synonyms: 桑辛素P)

Moracin P Chemical Structure

CAS No. : 102841-46-3

规格		是否有货
5 mg		询价
10 mg		询价
25 mg		询价

* Please select Quantity before adding items.

生物活性	Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin P reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects^[1]^[2]^[3].
体外研究 (In Vitro)	Moracin P enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC₅₀ value of 10.4 μM. Moracin P reduces ROS production in OGD-induced cell death (IC₅₀ values of 1.9 μM). Consequently, reactive oxygen species (ROS) are overexpressed in OGD-induced cells and Moracin P reduces ROS induced by OGD in dosedependent manner^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	326.34
Formula	C₁₉H₁₈O₅
CAS 号	102841-46-3
中文名称	桑辛素P
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Moracin O(Synonyms: 桑辛素O)

发表于2024年1月4日由上海金畔生物科技有限公司

Moracin O (Synonyms: 桑辛素O)

Moracin O Chemical Structure

CAS No. : 123702-97-6

规格	价格	是否有货
5 mg	￥3700	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	Moracin O is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects^[1]^[2]^[3].
体外研究 (In Vitro)	Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC₅₀ value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC₅₀ value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	326.34
Formula	C₁₉H₁₈O₅
CAS 号	123702-97-6
中文名称	桑辛素O
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Moracin O(Synonyms: 桑辛素O)

发表于2024年1月4日由上海金畔生物科技有限公司

Moracin O (Synonyms: 桑辛素O)

Moracin O Chemical Structure

CAS No. : 123702-97-6

规格	价格	是否有货
5 mg	￥3700	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	Moracin O is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects^[1]^[2]^[3].
体外研究 (In Vitro)	Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC₅₀ value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC₅₀ value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	326.34
Formula	C₁₉H₁₈O₅
CAS 号	123702-97-6
中文名称	桑辛素O
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Hak Ju Lee, et al. Inhibitory effect of 2-arylbenzofurans from the Mori Cortex Radicis (Moraceae) on oxygen glucose deprivation (OGD)-induced cell death of SH-SY5Y cells. Arch Pharm Res. 2011 Aug;34(8):1373-80. [2]. Yan Xia, et al. HIF-1α inhibitors: synthesis and biological evaluation of novel moracin O and P analogues. Eur J Med Chem. 2011 Jun;46(6):2386-96. [3]. Besse Hardianti, et al. Anti-inflammatory compounds moracin O and P from Morus alba Linn. (Sohakuhi) target the NF‑κB pathway. Mol Med Rep. 2020 Dec;22(6):5385-5391.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

桑辛素M对照品

发表于2024年1月3日由上海金畔生物科技有限公司

桑辛素M对照品

【编号】：SPR03672

【产品名称】：桑辛素M对照品

【规格】：10mg

【用途】：

　　桑辛素M对照品

　　编号：SPR03672

　　英文名称：Moracin M

　　英文别名：1,3-benzenediol, 5-(6-hydroxy-2-benzofuranyl)-; 5-(6-Hydroxy-1-benzofuran-2-yl)benzene-1,3-diol; 5-(6-Hydroxy-benzofuran-2-yl)-benzene-1,3-diol

　　CAS No.：56317-21-6

　　分子式：C14H10O4

　　分子量：242.23

　　类别：上海金畔生物科技有限公司，天然提取物

　　作为标准品，对照品或者供研究用，不能直接用于人体。

桑辛素P对照品

发表于2024年1月1日由上海金畔生物科技有限公司

桑辛素P对照品

【编号】：SPR02869

【产品名称】：桑辛素P对照品

【规格】：10mg

【用途】：

　　桑辛素P对照品

　　编号：SPR02869

　　英文名称：Moracin P

　　CAS No.：102841-46-3

　　分子式：C19H18O5

　　分子量：326.348

　　类别：上海金畔生物科技有限公司，天然提取物

　　作为标准品，对照品或者供研究用，不能直接用于人体。

桑辛素O对照品

发表于2024年1月1日由上海金畔生物科技有限公司

桑辛素O对照品

【编号】：SPR02860

【产品名称】：桑辛素O对照品

【规格】：10mg

【用途】：

　　桑辛素O对照品

　　编号：SPR02860

　　英文名称：Moracin O

　　CAS No.：123702-97-6

　　分子式：C19H18O5

　　分子量：326.348

　　类别：上海金畔生物科技有限公司，天然提取物

　　作为标准品，对照品或者供研究用，不能直接用于人体。

桑辛素C对照品

发表于2023年12月29日由上海金畔生物科技有限公司

桑辛素C对照品

【编号】：SPR01975

【产品名称】：桑辛素C对照品

【规格】：10mg

【用途】：

　　桑辛素C对照品

　　编号：SPR01975

　　英文名称：Moracin C

　　CAS No.：69120-06-5

　　分子式：C19H18O4

　　分子量：310.349

　　类别：上海金畔生物科技有限公司，天然提取物

　　作为标准品，对照品或者供研究用，不能直接用于人体。

Morusin(Synonyms: 桑辛素; Mulberrochromene)

发表于2023年10月6日由上海金畔生物科技有限公司

Morusin (Synonyms: 桑辛素; Mulberrochromene) 纯度: 99.83%

Morusin是从M. australis分离的去乙烯基化黄酮，具有抗肿瘤，抗氧化，抗菌等各种生物活性。Morusin可抑制 NF-κB 和 STAT3 的活性。

Morusin Chemical Structure

CAS No. : 62596-29-6

规格	价格	是否有货
10 mM * 1 mL in DMSO	￥1249	In-stock
2 mg	￥660	In-stock
5 mg	￥1350	In-stock
10 mg	￥2100	In-stock
25 mg	￥4200	In-stock
50 mg		询价
100 mg		询价

* Please select Quantity before adding items.

Morusin 相关产品

•相关化合物库:

Natural Product Library Plus
Bioactive Compound Library Plus
Anti-Infection Compound Library
Immunology/Inflammation Compound Library
JAK/STAT Compound Library
Kinase Inhibitor Library
NF-κB Signaling Compound Library
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生物活性

Morusin is a prenylated flavonoid isolated from M. australis with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.

IC₅₀ & Target^[1]^[3]

p65

STAT3

体外研究
(In Vitro)

Morusin exhibits a dose- and time-dependent inhibitory effect on murine and human breast cancer cells. IC₅₀ is 9.48 μg/mL for normal mammary epithelial cells (MCF-10A); 2.03 and 1.87 μg/mL for murine breast cancer cells (4 T1 and EMT6); and 2.71 and 3.86 μg/mL for human breast cancer cells (MCF-7 and MDA-MB-231), respectively, the maximal inhibition of cell growth (>80 %) is obtained at 8 μg/mL. The apoptotic cells in morusin treated breast cancer cells are increased significantly in a dose-dependent manner^[1]. Morusin significantly inhibits the growth and clonogenicity of human colorectal cancer HT-29 cells. Morusin also inhibits the phosphorylation of IKK-α, IKK-βand IκB-β, increases expression of IκB-α, and suppresses nuclear translocation of NF-κB and its DNA binding activity. Dephosphorylation of NF-κB upstream regulators PI3K, Akt and PDK1 is also displayed. In addition, activation of caspase-8, change of mitochondrial membrane potential, release of cytochrome c and Smac/DIABLO, and activation of caspase-9 and -3 are observed at the early time point. Downregulation in the expression of Ku70 and XIAP is exhibited afterward^[2]. Morusin suppresses viability of prostate cancer cells, but little effect in normal human prostate epithelial cells. Morusin also reduces STAT3 activity by inhibiting its phosphorylation, nuclear accumulation, and DNA binding activity. In addition, morusin down-regulated expression of STAT3 target genes encoding Bcl-xL, Bcl-2, Survivin, c-Myc and Cyclin D1. It induces apoptosis in human prostate cancer cells by reducing STAT3 activity^[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Morusin retards the growth of breast cancer significantly. Mean tumor weight of the control mice is 1.14±0.30 g, and those of the mice administrated with 5 and 10 mg/kg of morusin are 0.61±0.23 and 0.41±0.10 g, respectively, tumor inhibitory rates are 46.5 %, and 64.1 %, respectively^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

420.45

Formula

C₂₅H₂₄O₆

CAS 号

62596-29-6

中文名称

桑辛素；桑根白皮素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : ≥ 100 mg/mL (237.84 mM)

* “≥” means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.3784 mL	11.8920 mL	23.7840 mL
5 mM	0.4757 mL	2.3784 mL	4.7568 mL
10 mM	0.2378 mL	1.1892 mL	2.3784 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.5 mg/mL (5.95 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (5.95 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.95 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (5.95 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明

*以上所有助溶剂都可在上海金畔生物科技有限公司网站选购。

参考文献

[1]. Li H, et al. Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis. J Exp Clin Cancer Res. 2015 Nov 4;34:137.

[2]. Lee JC, et al. Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells. Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42.

[3]. Lim SL, et al. Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells. Am J Cancer Res. 2014 Dec 15;5(1):289-99.

Cell Assay ^[1]	The cytotoxicity of morusin against human normal mammary epithelial cells and murine breast cancer cells (4 T1 and EMT6) and human breast cancer cells (MCF-7 and MDA-MB-231) is tested by modified MTT assay [23]. Cells are treated with various concentrations of morusin (1, 2, 4, 6 and 8 μg/mL). After treatment with morusin for 1, 2, 3, 4, and 5 days, 20 μL MTT (pH 4.7) is added to each well, and cultivated for another 4 h, 100 μL of 10 % SDS/0.01 N HCl is added and incubated at 37 °C overnight to dissolve the formazan. Absorbance is measured at 570 nm^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Administration ^[1]	Mice: Two treatment group mice are injected with 5 and 10 mg/kg of morusin i.p. three times weekly for 4 weeks, respectively, and the control mice are injected with DMSO. During the experiment, mice are weighted, and tumor volumes are measured weekly using calipers and their volumes are calculated^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Li H, et al. Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis. J Exp Clin Cancer Res. 2015 Nov 4;34:137. [2]. Lee JC, et al. Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells. Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42. [3]. Lim SL, et al. Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells. Am J Cancer Res. 2014 Dec 15;5(1):289-99.

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桑辛素O对照品_123702-97-6

发表于2023年8月28日由上海金畔生物科技有限公司

桑辛素O对照品

【编号】：VIP(DS)1323

【产品名称】：桑辛素O对照品

【规格】：5mg；HPLC≥98%

【用途】：

　　桑辛素O对照品

　　编号：VIP(DS)1323

　　英文名： Moracin O

　　CAS号：123702-97-6

　　分子式： C19H18O5

　　分子量： 326.34

　　规格： 5mg/支

　　纯度： HPLC≥98%

　　用途：用于含量测定/鉴定/药理实验等

　　鉴别方法： NMR，MS

　　贮存条件： 4℃冷藏、密封、避光

　　规格：可定做：10mg；25mg；50mg；100mg

　　声明：此对照品、标准品由上海金畔生物科技有限公司提供查询购买服务

　　注：点击cas，或者搜索：名称、编号、cas均可查询产品信息

桑辛素P对照品_102841-46-3

发表于2023年8月28日由上海金畔生物科技有限公司

桑辛素P对照品

【编号】：VIP(DS)1322

【产品名称】：桑辛素P对照品

【规格】：5mg；HPLC≥98%

【用途】：

　　桑辛素P对照品

　　编号：VIP(DS)1322

　　英文名： Moracin P

　　CAS号：102841-46-3

　　分子式： C19H18O5

　　分子量： 326.34

　　规格： 5mg/支

　　纯度： HPLC≥98%

　　用途：用于含量测定/鉴定/药理实验等

　　鉴别方法： NMR，MS

　　贮存条件： 4℃冷藏、密封、避光

　　规格：可定做：10mg；25mg；50mg；100mg

　　声明：此对照品、标准品由上海金畔生物科技有限公司提供查询购买服务

　　注：点击cas，或者搜索：名称、编号、cas均可查询产品信息

桑辛素C对照品_69120-06-5

发表于2023年7月1日由上海金畔生物科技有限公司

桑辛素C对照品

【编号】：VIP(XL)01975

【产品名称】：桑辛素C对照品

【规格】：5mg

【用途】：

　　桑辛素C对照品

　　编号：VIP(XL)01975

　　英文：Moracin C

　　CAS号：69120-06-5

　　分子式：C19H18O4
桑辛素C对照品_69120-06-5

　　规格：可定做：10mg；25mg；50mg；100mg

　　声明：此对照品、标准品由上海金畔生物科技有限公司提供网站查询购买服务

　　注：点击cas，或者搜索：名称、编号、cas均可查询产品信息

桑辛素M对照品_56317-21-6

发表于2023年6月22日由上海金畔生物科技有限公司

桑辛素M对照品

【编号】：VIP(XL)03672

【产品名称】：桑辛素M对照品

【规格】：5mg

【用途】：

　　桑辛素M对照品

　　编号：VIP(XL)03672

　　英文：Moracin M

　　CAS号: 56317-21-6

　　分子式：C14H10O4
桑辛素M对照品_56317-21-6

　　性状：棕色粉末

　　纯度：97.0%

　　规格：可定做：10mg；25mg；50mg；100mg

　　声明：此对照品、标准品由上海金畔生物科技有限公司提供网站查询购买服务

　　注：点击cas，或者搜索：名称、编号、cas均可查询产品信息

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标签归档：桑辛素

桑辛素对照品

桑辛素对照品

Moracin P(Synonyms: 桑辛素P)

Moracin O(Synonyms: 桑辛素O)

Moracin P(Synonyms: 桑辛素P)

Moracin P(Synonyms: 桑辛素P)

Moracin O(Synonyms: 桑辛素O)

Moracin O(Synonyms: 桑辛素O)

桑辛素M对照品

桑辛素M对照品

桑辛素P对照品

桑辛素P对照品

桑辛素O对照品

桑辛素O对照品

桑辛素C对照品

桑辛素C对照品

Morusin(Synonyms: 桑辛素; Mulberrochromene)

Morusin 相关产品

•相关化合物库:

桑辛素O对照品_123702-97-6

桑辛素O对照品

桑辛素P对照品_102841-46-3

桑辛素P对照品

桑辛素C对照品_69120-06-5

桑辛素C对照品

桑辛素M对照品_56317-21-6

桑辛素M对照品

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