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Cinobufagin (Synonyms: 华蟾蜍精; Cinobufagine) 纯度: 98.90%
华蟾酥毒基 (Cinobufagin)是一种天然化合物,具有抗肿瘤的功效。
Cinobufagin Chemical Structure
CAS No. : 470-37-1
规格 | 价格 | 是否有货 | 数量 |
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10 mM * 1 mL in DMSO | ¥1430 | In-stock | |
5 mg | ¥1300 | In-stock | |
10 mg | ¥2350 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
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Cinobufagin 相关产品
•相关化合物库:
- Covalent Screening Library Plus
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- Apoptosis Compound Library
- Natural Product Library
- Anti-Cancer Compound Library
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- Covalent Screening Library
- Lipid Compound Library
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生物活性 |
Cinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer. IC50 value: Target: In vitro: Cinobufagin inhibited proliferation of cancer cells at doses of 0.1, 1, or 10 μM after 2–4 days of culture. Cytotoxicity of cinobufagin on the DU145 and LNCaP cells was dose-dependent. Cinobufagin increased [Ca2+]i and apoptosis in cancer cells after a 24-hr culture as well as caspase 3 activities in DU145 and PC3 cells and caspase 9 activities in LNCaP cells [1]. Cinobufagin suppresses cell proliferation and causees apoptosis in prostate cancer cells via a sequence of apoptotic modulators, including Bax, cytochrome c and caspases [2]. In vivo: |
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分子量 |
442.54 |
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Formula |
C26H34O6 |
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CAS 号 |
470-37-1 |
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中文名称 |
华蟾蜍精;华蟾毒精;华蟾酥毒基 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : ≥ 100 mg/mL (225.97 mM) * “≥” means soluble, but saturation unknown. 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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