标签归档：hydrazine

(2-pyridyldithio)-PEG1-hydrazine

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

(2-pyridyldithio)-PEG1-hydrazine 

(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

规格 价格 是否有货 数量
50 mg ￥1500 In-stock
100 mg ￥2400 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

187.28

Formula

C7H9NOS2
CAS 号

111625-28-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG1-hydrazine

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

(2-pyridyldithio)-PEG1-hydrazine 

(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

规格 价格 是否有货 数量
50 mg ￥1500 In-stock
100 mg ￥2400 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

187.28

Formula

C7H9NOS2
CAS 号

111625-28-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG1-hydrazine

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

(2-pyridyldithio)-PEG1-hydrazine 

(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

规格 价格 是否有货 数量
50 mg ￥1500 In-stock
100 mg ￥2400 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

187.28

Formula

C7H9NOS2
CAS 号

111625-28-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

MC-Alkyl-Hydrazine Modified MMAF

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

MC-Alkyl-Hydrazine Modified MMAF 

MC-Alkyl-Hydrazine Modified MMAF 是抗体偶联药物的一部分 (drug-linker conjugate for ADC)，具有抗癌活性，是由修饰过的 MMAF (一种微管蛋白抑制剂) 和不可降解 (non-cleavable) 的 MC-Alkyl-Hydrazine linker 连接而成。

MC-Alkyl-Hydrazine Modified MMAF

MC-Alkyl-Hydrazine Modified MMAF Chemical Structure

CAS No. : 1404071-64-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

MC-Alkyl-Hydrazine Modified MMAF is a drug-linker conjugate for ADC with potent antitumor activity by using the Modified MMAF (a tubulin inhibitor), linked via the noncleavable MC-Alkyl-Hydrazine[1].

IC50 & Target[1]

Auristatin

 

分子量

1133.42

Formula

C59H92N10O12
CAS 号

1404071-64-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务