SPDP (Succinimidyl 3-[2-pyridyldithio] propionate) Cat. No. SPD01 20 mg修饰性聚乙二醇

发表于2024年4月26日由上海金畔生物科技有限公司

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

SPDP (Succinimidyl 3-[2-pyridyldithio] propionate)

Cat. No.	SPD01
Specification
Unit Size	20 mg
Price	$325.00

SPDP Crosslinker Description:

Nanocs SnapLink^TMSPDP crosslinker, N–Succinimidyl 3-(2-pyridyldithio) propionic acid, also called N-succinimidyl 3-(2-pyridyldithio)-propionate, or OPSS-NHS, is a short-length crosslinker for amine to sulfhydryl (thiol) conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups. Nanocs LC-SPDP is a long-length crossliker for amine to sulfhydryl conjugation via its NHS-ester and pyridyldithiol reactive groups that form cleavable disulfide bonds with free thiol groups.

In addition to above hydrophobic SPDP crosslinker, Nanocs also offer water-soluble SPDP crosslinker either with sulfonated NHS (Sulfo-SPDP) or Pegylated SPDP crosslinker, such as our PEG OPSS products. These SPDP crosslinkers are heterobifunctional and thiol cleavable crosslinkers.

SPDP Crosslinker Physical Properties:

Appearance: Off-white/white solid;
Reactive groups: NHS ester and pyridyldithiol;
Reactive towards: amino (amine) and sulfhydryl (thiol) groups;
SPDP crosslinker is membrane permeable;
Solubility: Soluble in DMF or DMSO;

SPDP Applications:

Adding thiol/sulfhydryl groups to proteins, antibodies or other molecules by reacting with amine groups;
Reversible crosslinking of proteins or other molecules;

SPDP Storage Conditions:

Store at -20 ⁰C, desicate. Avoid frequent thaw and freeze.

3-(2-Pyridyldithio)propanoic Acid

发表于2024年2月21日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

3-(2-Pyridyldithio)propanoic Acid 纯度: 98.36%

3-(2-Pyridyldithio)propanoic Acid 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

3-(2-Pyridyldithio)propanoic Acid Chemical Structure

CAS No. : 68617-64-1

规格	价格	是否有货
50 mg	￥500	In-stock
100 mg	￥800	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

Alkyl-Chain

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

215.29

Formula

C₈H₉NO₂S₂

CAS 号

68617-64-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

溶解性数据

In Vitro:

DMSO : 250 mg/mL (1161.22 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.6449 mL	23.2245 mL	46.4490 mL
5 mM	0.9290 mL	4.6449 mL	9.2898 mL
10 mM	0.4645 mL	2.3224 mL	4.6449 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.08 mg/mL (9.66 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (9.66 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (9.66 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (9.66 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil

Solubility: ≥ 2.08 mg/mL (9.66 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (9.66 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG2-Boc

发表于2024年2月21日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG2-Boc

(2-Pyridyldithio)-PEG2-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

(2-Pyridyldithio)-PEG2-Boc Chemical Structure

CAS No. : 2144777-73-9

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性

(2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs	Alkyl/ether

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

359.50

Formula

C₁₆H₂₅NO₄S₂

CAS 号

2144777-73-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG4-propargyl

发表于2024年2月14日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG4-propargyl

(2-Pyridyldithio)-PEG4-propargyl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

(2-Pyridyldithio)-PEG4-propargyl Chemical Structure

CAS No. : 2170240-99-8

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

357.49

Formula

C₁₆H₂₃NO₄S₂

CAS 号

2170240-99-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG4-propargyl

发表于2024年2月14日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG4-propargyl

(2-Pyridyldithio)-PEG4-propargyl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

(2-Pyridyldithio)-PEG4-propargyl Chemical Structure

CAS No. : 2170240-99-8

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-Pyridyldithio)-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

357.49

Formula

C₁₆H₂₃NO₄S₂

CAS 号

2170240-99-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG4-alcohol

发表于2024年2月13日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG4-alcohol

(2-Pyridyldithio)-PEG4-alcohol 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

(2-Pyridyldithio)-PEG4-alcohol Chemical Structure

CAS No. : 851961-99-4

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

319.44

Formula

C₁₃H₂₁NO₄S₂

CAS 号

851961-99-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG4-alcohol

发表于2024年2月12日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG4-alcohol

(2-Pyridyldithio)-PEG4-alcohol 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

(2-Pyridyldithio)-PEG4-alcohol Chemical Structure

CAS No. : 851961-99-4

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-Pyridyldithio)-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

体外研究
(In Vitro)

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

319.44

Formula

C₁₃H₂₁NO₄S₂

CAS 号

851961-99-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG1-hydrazine

发表于2024年1月30日由上海金畔生物科技有限公司

(2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

规格	价格	是否有货
50 mg	￥1500	In-stock
100 mg	￥2400	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

187.28

Formula

C₇H₉NOS₂

CAS 号

111625-28-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG1-hydrazine

发表于2024年1月30日由上海金畔生物科技有限公司

(2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

规格	价格	是否有货
50 mg	￥1500	In-stock
100 mg	￥2400	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

187.28

Formula

C₇H₉NOS₂

CAS 号

111625-28-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG1-hydrazine

发表于2024年1月30日由上海金畔生物科技有限公司

(2-pyridyldithio)-PEG1-hydrazine

(2-pyridyldithio)-PEG1-hydrazine 是一种可降解 (cleavable) 的含 1 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG1-hydrazine Chemical Structure

CAS No. : 111625-28-6

规格	价格	是否有货
50 mg	￥1500	In-stock
100 mg	￥2400	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

187.28

Formula

C₇H₉NOS₂

CAS 号

111625-28-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG6 acid

发表于2024年1月16日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG6 acid

2-Pyridyldithio-PEG6 acid 是一种可降解 (cleavable) 的含 6 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-Pyridyldithio)-PEG6 acid Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

479.61

Formula

C₂₀H₃₃NO₈S₂

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG6 acid

发表于2024年1月16日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG6 acid

2-Pyridyldithio-PEG6 acid 是一种可降解 (cleavable) 的含 6 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-Pyridyldithio)-PEG6 acid Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

479.61

Formula

C₂₀H₃₃NO₈S₂

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-Pyridyldithio)-PEG6 acid

发表于2024年1月16日由上海金畔生物科技有限公司

(2-Pyridyldithio)-PEG6 acid

2-Pyridyldithio-PEG6 acid 是一种可降解 (cleavable) 的含 6 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-Pyridyldithio)-PEG6 acid Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

2-Pyridyldithio-PEG6 acid is a cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

479.61

Formula

C₂₀H₃₃NO₈S₂

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG4 acid

发表于2023年11月11日由上海金畔生物科技有限公司

(2-pyridyldithio)-PEG4 acid

(2-pyridyldithio)-PEG4 acid 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG4 acid Chemical Structure

CAS No. : 581065-93-2

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

391.50

Formula

C₁₆H₂₅NO₆S₂

CAS 号

581065-93-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG4 acid

发表于2023年11月11日由上海金畔生物科技有限公司

(2-pyridyldithio)-PEG4 acid

(2-pyridyldithio)-PEG4 acid 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG4 acid Chemical Structure

CAS No. : 581065-93-2

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

391.50

Formula

C₁₆H₂₅NO₆S₂

CAS 号

581065-93-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(2-pyridyldithio)-PEG4 acid

发表于2023年11月11日由上海金畔生物科技有限公司

(2-pyridyldithio)-PEG4 acid

(2-pyridyldithio)-PEG4 acid 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

(2-pyridyldithio)-PEG4 acid Chemical Structure

CAS No. : 581065-93-2

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

(2-pyridyldithio)-PEG4 acid is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1].

IC₅₀ & Target

Cleavable

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

391.50

Formula

C₁₆H₂₅NO₆S₂

CAS 号

581065-93-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

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标签归档：pyridyldithio

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