苄星青霉素

某些青霉菌株或相关霉菌产生的抗微生物酸的衍生物。用于治疗由于敏感生物引起的各种感染，包括伤口感染，脓肿，bo疮，白喉，急性扁桃体炎等。对大多数革兰氏阳性细菌和革兰氏阴性球菌具有抑菌和杀菌作用。被认为通过抑制转肽酶起作用，转肽酶是在细菌细胞壁合成的最后阶段负责肽聚糖交联的酶。

Derivative of an antimicrobial acid produced by certain strains of Penicillium notatum or related moulds. Used in the treatment of a variety of infections due to susceptible organisms, including wound infections, abscesses, boils, diphtheria, acute tonsillitis etc. Has bacteriostatic and bacteriocidal actions against most Gram-positive bacteria and Gram-negative cocci. thought to act by inhibiting transpeptidase, the enzyme responsible for the cross-linking of peptidoglycan during the final stages of synthesis of the bacterial cell wall.

11-O-甲基拟青霉素A

11-O-甲基拟青霉素A是一种抑制Hof1缺失菌株的抗菌剂。

11-O-Methylpseurotin A is an antibacterial that inhibits a Hof1 deletion strain.

鲜绿青霉素

Viridicatin是从几种青霉菌中分离得到的3-羟基-4-芳基喹啉-2（1H）-一种真菌代谢产物。文献报道中尚未探讨维立他汀的作用机理。Viridicatin具有抗结核分枝杆菌的功效。

Viridicatin is a 3-hydroxy-4-arylquinolin-2(1H)-one fungal metabolite isolated from several|Penicillium|species. The mechanism of action of Viridicatin remains unexplored in literature reports. Viridicatin demonstrates efficacy against|Mycobacterium tuberculosis|.

2-溴羧青霉素二钠盐

17β-羟基渥曼青霉素

17β-hydroxy Wortmannin 是渥曼青霉素的类似物。它不可逆地结合PI 3-激酶，并有效阻断中性粒细胞中由fMLP刺激的呼吸爆发（IC | 50 | = 5 nM）。17β-羟基Wortmannin抑制重组PI 3-激酶和mTOR（分别为IC | 50 | = 2.7和193 nM）并阻止LNCap前列腺癌细胞的生长（IC | 50 | = 1.46μM）。17-羟基已用于进一步修饰该化合物，例如通过聚乙二醇化和与雷帕霉素缀合。

17β-hydroxy Wortmannin is an analog of wortmannin . It irreversibly binds PI 3-kinase and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC|50|= 5 nM). 17β-hydroxy Wortmannin inhibits recombinant PI 3-kinase and mTOR (IC|50|= 2.7 and 193 nM, respectively) and prevents the growth of LNCap prostate cancer cells (IC|50|= 1.46 μM). The 17-hydroxyl group has been used to further modify this compound, e.g., by pegylation and conjugation with rapamycin .

4′-溴氨苄青霉素

羧苄青霉素溶液

羧苄青霉素溶液是羧苄青霉素二钠的溶液形式。羧苄青霉素是一种氨苄青霉素类似物，即使在低pH值下也能抑制细菌细胞壁的合成。羧苄青霉素也比氨苄青霉素对β-内酰胺酶降解的抵抗力更强，可与耐氨苄青霉素的铜绿假单胞菌，革兰氏阳性菌和革兰氏阴性菌一起使用。

Carbenicillin solution is the solution form of Carbenicillin disodium (sc-202519B). Carbenicillin is an ampicillin analog that inhibits bacterial cell wall synthesis even at low pH. Carbenicillin also tends to be more resistant to β-lactamase enzyme degradation than ampicillin and can be used with ampicillin-resistant strains of|Pseudomonas aerogenosa|, gram-positive, and gram-negative bacteria.
Carbenicillin solutionis an ampicillin analog stable at low pH

核丛青霉素

核丛青霉素是主要从青霉属中分离的天然产物。它以4.2μM的IC |值抑制大豆脂氧合酶-1。硬化蛋白还表现出许多其他活性，包括抑制CETP（胆固醇酯转移蛋白，IC | 50 | = 19.4μM），抑制Grb2-Shc相互作用（IC | 50 | = 22μM）以及对ETAR和ETBR的拮抗作用（内皮细胞受体），其对于人细胞的IC | 50 | = 114和152μM。

Sclerotiorin is a natural product isolated primarily from|Penicillium|species. It inhibits soybean lipoxygenase-1 with an IC|50|value of 4.2 μM. Sclerotiorin also exhibits a number of other activities encompassing inhibition of CETP (cholesterol ester transfer protein, IC|50|= 19.4 μM), inhibition of Grb2-Shc interaction (IC|50|= 22 μM), and antagonism of ETAR and ETBR (endothelin receptors) with respective IC|50|= 114 and 152 μM for human cells.

羧苄青霉素钠

Information

Carbenicillin (BRL-2064) is a semi-synthetic penicillin antibiotic which interferes with cell wall synthesis of gram-negative bacteria while displaying low toxicity.
In vitro

Carbenicillin (125 mg/L) completely suppresses the proliferation of Agrobacterium. Carbenicillin (250 mg/L-500 mg/L) enhances Callus fresh weight increase. Carbenicillin (125 mg/L) results in higher percentages of somatic embryos and larger numbers of somatic embryos from the individual callus. Carbenicillin (1g/L) influences shoot formation negatively as the shooting frequency for leaf disc explants is reduced to 56% and for cotyledons to 51% after 2 months of culture of Nicotiana tabacum Petit Havana. Carbenicillin prevents the development of mature somatic embryos, reduces early stage embryos by >90% and tissue growth by 50% of Sitka spruce. The leukocytes of the patients does not release histamine on in vitro provocation with Carbenicillin (0.1 g/mL).

In vivo

Carbenicillin (0.1 g/mL) does not show any allergic drug reactions in cystic fibrosis patients, as evident by no significant levels of antibodies of IgE, IgG or IgM classes. Carbenicillin (50 μg/mL) results in phytotoxicity in chrysanthemum and TOB, with an increase in the concentration, and with a parallel shift in the morphogenic capacity (SRC) of threshold survival levels (TSLs). Carbenicillin results in 100% acclimatization with no different morphological flowering characteristics following subculture in vitro three times in Chrysanthemum plantlets.
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:

氨苄青霉素，三水

微溶于水和甲醇,几乎不溶于氯仿、乙醚、丙酮和四氯化碳,无臭、味苦,其钠盐易溶于水。

青霉素钾

青霉素G苄星盐

某些青霉菌株或相关霉菌产生的抗微生物酸的衍生物。用于治疗由于敏感生物引起的各种感染，包括伤口感染，脓肿，bo疮，白喉，急性扁桃体炎等。对大多数革兰氏阳性细菌和革兰氏阴性球菌具有抑菌和杀菌作用。被认为通过抑制转肽酶起作用，转肽酶是在细菌细胞壁合成的最后阶段负责肽聚糖交联的酶。

Derivative of an antimicrobial acid produced by certain strains of Penicillium notatum or related moulds. Used in the treatment of a variety of infections due to susceptible organisms, including wound infections, abscesses, boils, diphtheria, acute tonsillitis etc. Has bacteriostatic and bacteriocidal actions against most Gram-positive bacteria and Gram-negative cocci. thought to act by inhibiting transpeptidase, the enzyme responsible for the cross-linking of peptidoglycan during the final stages of synthesis of the bacterial cell wall.

青霉素G钠

溶于水,分解点为215℃，极易溶于水，溶于乙醇，不溶于脂肪油液体石蜡。有吸湿性，遇酸、碱、氧化剂、青霉素酶等均能使青霉素的β-内酰胺环打开而失效。

application：

Penicillin G sodium salt is used as a β-lactam antibiotic. Penicillin G can be used as a selective agent in several types of isolation media. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

青霉素/链霉素溶液

产品介绍：（10000U/mL青霉素+10000μg/mL链霉素）