KRAS G12C inhibitor 20

发表于2023年12月5日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

KRAS G12C inhibitor 20

KRAS G12C inhibitor 20 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 CN112694475A 中的实施例 1。

KRAS G12C inhibitor 20 Chemical Structure

CAS No. : 2640858-10-0

规格		是否有货
100 mg		询价
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500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 20 is a KRAS G12C inhibitor extracted from patent CN112694475A, example 1^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	634.14
Formula	C₃₃H₃₇ClFN₇O₃
CAS 号	2640858-10-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Cycloalkyl and heterocycloalkyl inhibitors, and preparation method and application thereof. CN112694475A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 21

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 21

KRAS G12C inhibitor 21 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 WO2021219090A1 中的实施例 7。

KRAS G12C inhibitor 21 Chemical Structure

CAS No. : 2737269-61-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 21 is a KRAS G12C inhibitor extracted from patent WO2021219090A1, example 7^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	580.07
Formula	C₃₄H₃₀ClN₃O₄
CAS 号	2737269-61-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Quinoxaline dione derivative as irreversible inhibitor of kras g12c mutant protein. WO2021219090A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 22

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 22

KRAS G12C inhibitor 22 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 WO2021219072A1 中的实施例 120。

KRAS G12C inhibitor 22 Chemical Structure

CAS No. : 2736599-72-5

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 22 is a KRAS G12C inhibitor extracted from patent WO2021219072A1, example 120^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	555.71
Formula	C₃₂H₄₁N₇O₂
CAS 号	2736599-72-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Preparation and application method of heterocyclic compound as kras inhibitor. WO2021219072A1.

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KRAS G12C inhibitor 23

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 23

KRAS G12C inhibitor 23 是 KRAS G12C 抑制剂。KRAS G12C inhibitor 23 抑制H358 细胞的 IC₅₀ 为 491 nM (WO2021218939A1, compound 1)。

KRAS G12C inhibitor 23 Chemical Structure

CAS No. : 2735721-00-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC₅₀ of 491 nM (WO2021218939A1, compound 1)^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

553.63

Formula

C₃₂H₃₂FN₅O₃

CAS 号

2735721-00-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Fused ring compound and application thereof in medicine. WO2021218939A1.

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KRAS G12C inhibitor 24

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 24

KRAS G12C inhibitor 24 是一种有效 KRAS G12C 抑制剂。KRAS G12C inhibitor 24 抑制 KRAS G12C/SOS1 相互作用，IC₅₀ 小于 50 nM (CN113563323A, compound 1)。

KRAS G12C inhibitor 24 Chemical Structure

CAS No. : 2735742-75-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 24 is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 24 inhibits KRAS G12C/SOS1 interaction with an IC₅₀ of＜50 nM (CN113563323A, compound 1)^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

600.08

Formula

C₂₈H₂₈ClF₂N₇O₂S

CAS 号

2735742-75-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Benzothiazolyl biaryl compounds, preparation method and application. CN113563323A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 25

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 25

KRAS G12C inhibitor 25 是 KRAS G12C 抑制剂。KRAS G12C inhibitor 25 抑制 KRAS-G12C 突变体的 SOS1 辅助的 GDP/GTP 交换活性 (IC₅₀=0.48 nM)。详细信息请参加专利 WO2021216770A1 compound 3。

KRAS G12C inhibitor 25 Chemical Structure

CAS No. : 2734060-73-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 25 is a KRAS G12C inhibitor. KRAS G12C inhibitor 25 inhibits SOSl-assisted GDP/GTP exchanging activity of KRAS-G12C mutant (IC₅₀=0.48 nM). From WO2021216770A1 compound 3^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

555.71

Formula

C₃₂H₄₁N₇O₂

CAS 号

2734060-73-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Yimin Qian, et al. Substituted tetrahydroquinazoline compounds as kras inhibitors. WO2021216770A1.

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KRAS G12C inhibitor 20

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 20

KRAS G12C inhibitor 20 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 CN112694475A 中的实施例 1。

KRAS G12C inhibitor 20 Chemical Structure

CAS No. : 2640858-10-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 20 is a KRAS G12C inhibitor extracted from patent CN112694475A, example 1^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	634.14
Formula	C₃₃H₃₇ClFN₇O₃
CAS 号	2640858-10-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Cycloalkyl and heterocycloalkyl inhibitors, and preparation method and application thereof. CN112694475A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 21

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 21

KRAS G12C inhibitor 21 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 WO2021219090A1 中的实施例 7。

KRAS G12C inhibitor 21 Chemical Structure

CAS No. : 2737269-61-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 21 is a KRAS G12C inhibitor extracted from patent WO2021219090A1, example 7^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	580.07
Formula	C₃₄H₃₀ClN₃O₄
CAS 号	2737269-61-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Quinoxaline dione derivative as irreversible inhibitor of kras g12c mutant protein. WO2021219090A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 22

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 22

KRAS G12C inhibitor 22 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 WO2021219072A1 中的实施例 120。

KRAS G12C inhibitor 22 Chemical Structure

CAS No. : 2736599-72-5

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 22 is a KRAS G12C inhibitor extracted from patent WO2021219072A1, example 120^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	555.71
Formula	C₃₂H₄₁N₇O₂
CAS 号	2736599-72-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Preparation and application method of heterocyclic compound as kras inhibitor. WO2021219072A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 20

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 20

KRAS G12C inhibitor 20 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 CN112694475A 中的实施例 1。

KRAS G12C inhibitor 20 Chemical Structure

CAS No. : 2640858-10-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 20 is a KRAS G12C inhibitor extracted from patent CN112694475A, example 1^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	634.14
Formula	C₃₃H₃₇ClFN₇O₃
CAS 号	2640858-10-0
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Cycloalkyl and heterocycloalkyl inhibitors, and preparation method and application thereof. CN112694475A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 23

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 23

KRAS G12C inhibitor 23 是 KRAS G12C 抑制剂。KRAS G12C inhibitor 23 抑制H358 细胞的 IC₅₀ 为 491 nM (WO2021218939A1, compound 1)。

KRAS G12C inhibitor 23 Chemical Structure

CAS No. : 2735721-00-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC₅₀ of 491 nM (WO2021218939A1, compound 1)^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

553.63

Formula

C₃₂H₃₂FN₅O₃

CAS 号

2735721-00-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Fused ring compound and application thereof in medicine. WO2021218939A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 21

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 21

KRAS G12C inhibitor 21 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 WO2021219090A1 中的实施例 7。

KRAS G12C inhibitor 21 Chemical Structure

CAS No. : 2737269-61-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 21 is a KRAS G12C inhibitor extracted from patent WO2021219090A1, example 7^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	580.07
Formula	C₃₄H₃₀ClN₃O₄
CAS 号	2737269-61-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Quinoxaline dione derivative as irreversible inhibitor of kras g12c mutant protein. WO2021219090A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 24

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 24

KRAS G12C inhibitor 24 是一种有效 KRAS G12C 抑制剂。KRAS G12C inhibitor 24 抑制 KRAS G12C/SOS1 相互作用，IC₅₀ 小于 50 nM (CN113563323A, compound 1)。

KRAS G12C inhibitor 24 Chemical Structure

CAS No. : 2735742-75-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 24 is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 24 inhibits KRAS G12C/SOS1 interaction with an IC₅₀ of＜50 nM (CN113563323A, compound 1)^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

600.08

Formula

C₂₈H₂₈ClF₂N₇O₂S

CAS 号

2735742-75-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Benzothiazolyl biaryl compounds, preparation method and application. CN113563323A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 22

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 22

KRAS G12C inhibitor 22 是一种 KRAS G12C 的抑制剂，详细信息请参考专利文献 WO2021219072A1 中的实施例 120。

KRAS G12C inhibitor 22 Chemical Structure

CAS No. : 2736599-72-5

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	KRAS G12C inhibitor 22 is a KRAS G12C inhibitor extracted from patent WO2021219072A1, example 120^[1].
IC₅₀ & Target	KRAS G12C^[1]
分子量	555.71
Formula	C₃₂H₄₁N₇O₂
CAS 号	2736599-72-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Preparation and application method of heterocyclic compound as kras inhibitor. WO2021219072A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 23

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 23

KRAS G12C inhibitor 23 是 KRAS G12C 抑制剂。KRAS G12C inhibitor 23 抑制H358 细胞的 IC₅₀ 为 491 nM (WO2021218939A1, compound 1)。

KRAS G12C inhibitor 23 Chemical Structure

CAS No. : 2735721-00-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC₅₀ of 491 nM (WO2021218939A1, compound 1)^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

553.63

Formula

C₃₂H₃₂FN₅O₃

CAS 号

2735721-00-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Fused ring compound and application thereof in medicine. WO2021218939A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 25

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 25

KRAS G12C inhibitor 25 Chemical Structure

CAS No. : 2734060-73-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

IC₅₀ & Target^[1]

KRas G12C

分子量

555.71

Formula

C₃₂H₄₁N₇O₂

CAS 号

2734060-73-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Yimin Qian, et al. Substituted tetrahydroquinazoline compounds as kras inhibitors. WO2021216770A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 24

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 24

KRAS G12C inhibitor 24 是一种有效 KRAS G12C 抑制剂。KRAS G12C inhibitor 24 抑制 KRAS G12C/SOS1 相互作用，IC₅₀ 小于 50 nM (CN113563323A, compound 1)。

KRAS G12C inhibitor 24 Chemical Structure

CAS No. : 2735742-75-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

KRAS G12C inhibitor 24 is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 24 inhibits KRAS G12C/SOS1 interaction with an IC₅₀ of＜50 nM (CN113563323A, compound 1)^[1].

IC₅₀ & Target^[1]

KRas G12C

分子量

600.08

Formula

C₂₈H₂₈ClF₂N₇O₂S

CAS 号

2735742-75-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Benzothiazolyl biaryl compounds, preparation method and application. CN113563323A.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

KRAS G12C inhibitor 25

发表于2023年12月5日由上海金畔生物科技有限公司

KRAS G12C inhibitor 25

KRAS G12C inhibitor 25 Chemical Structure

CAS No. : 2734060-73-0

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性

IC₅₀ & Target^[1]

KRas G12C

分子量

555.71

Formula

C₃₂H₄₁N₇O₂

CAS 号

2734060-73-0

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Yimin Qian, et al. Substituted tetrahydroquinazoline compounds as kras inhibitors. WO2021216770A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SOS1-IN-5

发表于2023年12月5日由上海金畔生物科技有限公司

SOS1-IN-5

SOS1-IN-5 是一种有效的 SOS1 抑制剂。SOS1-IN-5 是嘧啶双环衍生物。SOS1-IN-5通过干扰RAS-SOS1相互作用阻断KRAS的激活，达到广谱抑制KRAS活性的目的。SOS1-IN-5具有研究癌症疾病的潜力(信息提取自专利 WO2021203768A1，compound 4)。

SOS1-IN-5 Chemical Structure

CAS No. : 2716956-47-5

规格		是否有货
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500 mg		询价

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生物活性	SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)^[1].
分子量	536.54
Formula	C₂₆H₃₁F₃N₄O₅
CAS 号	2716956-47-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Xin Li, et al. Pyrimidobicyclic derivatives, their preparation method and their application in medicine. Patent WO2021203768A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SOS1-IN-5

发表于2023年12月4日由上海金畔生物科技有限公司

SOS1-IN-5

SOS1-IN-5 Chemical Structure

CAS No. : 2716956-47-5

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	SOS1-IN-5 is a potent inhibitor of SOS1. SOS1-IN-5 is a pyrimidobicyclic derivative. SOS1-IN-5 blocks the activation of KRAS by interfering with RAS-SOS1 interaction, and achieves the purpose of broad-spectrum inhibition of KRAS activity. SOS1-IN-5 has the potential for the research of cancer diseases (extracted from patent WO2021203768A1, compound 4)^[1].
分子量	536.54
Formula	C₂₆H₃₁F₃N₄O₅
CAS 号	2716956-47-5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Xin Li, et al. Pyrimidobicyclic derivatives, their preparation method and their application in medicine. Patent WO2021203768A1.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

赛默飞Alfa aesar官网

赛默飞Acros试剂中国官网 Alfa aesar阿法埃莎中国代理商

标签归档：kras

KRAS G12C inhibitor 20

KRAS G12C inhibitor 21

KRAS G12C inhibitor 22

KRAS G12C inhibitor 23

KRAS G12C inhibitor 24

KRAS G12C inhibitor 25

KRAS G12C inhibitor 20

KRAS G12C inhibitor 21

KRAS G12C inhibitor 22

KRAS G12C inhibitor 20

KRAS G12C inhibitor 23

KRAS G12C inhibitor 21

KRAS G12C inhibitor 24

KRAS G12C inhibitor 22

KRAS G12C inhibitor 23

KRAS G12C inhibitor 25

KRAS G12C inhibitor 24

KRAS G12C inhibitor 25

SOS1-IN-5

SOS1-IN-5