氯己定 二葡糖酸盐 溶液

Chlorhexidine digluconate solution是双（双胍）家族阳离子广谱抗生素。研究表明，Chlorhexidine digluconate solution通过细菌外膜的失稳而起作用，这导致革兰氏阴性细菌中的周质酶释放。另外，Chlorhexidine digluconate solution抑制氧气的利用，这导致细菌ATP的减少。这些研究还表明，革兰氏阴性细菌的内膜不受溶液的影响，但是对进入细胞的小分子的主动转运有抑制作用。进而，Chlorhexidine digluconate

Chlorhexidine digluconate solution is a bis(biguanide) family cationic broad spectrum antibiotic. Studies indicate that Chlorhexidine digluconate solution functions, via destabilization of the outer bacterial membrane, which resulted in the release of periplasmic enzymes in gram negative bacteria. In addition, Chlorhexidine digluconate solution inhibits oxygen utilization which leads to a reduction in bacterial ATP. These studies also indicate that the inner membrane in gram negative bacteria was not affected by the solution, however there was inhibition of active transport for small molecules entering the cell. Furthermore, Chlorhexidine digluconate solution is very effective against bacteria such as|Propionibacterium, Selenomonas|, and cocci resembling|Veillonella|.