Glycochenodeoxycholic acid-d7 sodium(Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

发表于2023年12月21日由上海金畔生物科技有限公司

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Glycochenodeoxycholic acid-d7 sodium (Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

Glycochenodeoxycholic acid-d7 (Chenodeoxycholylglycine-d7) sodium 是 Glycochenodeoxycholic acid (sodium salt) 的氘代物。Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐。它起到洗涤剂的作用，可溶解脂肪吸收，并本身被吸收。Glycochenodeoxy

Glycochenodeoxycholic acid-d7 sodium Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性	Glycochenodeoxycholic acid-d7 (Chenodeoxycholylglycine-d7) sodium is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	478.65
Formula	C₂₆H₃₅D₇NNaO₅
中文名称	甘氨鹅脱氧胆酸钠 d7 (钠盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [3]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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Glycochenodeoxycholic acid-d7 sodium(Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

发表于2023年12月20日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid-d7 sodium (Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

Glycochenodeoxycholic acid-d7 sodium Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	Glycochenodeoxycholic acid-d7 (Chenodeoxycholylglycine-d7) sodium is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	478.65
Formula	C₂₆H₃₅D₇NNaO₅
中文名称	甘氨鹅脱氧胆酸钠 d7 (钠盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [3]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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Glycochenodeoxycholic acid-d7 sodium(Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

发表于2023年12月20日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid-d7 sodium (Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

Glycochenodeoxycholic acid-d7 sodium Chemical Structure

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

* Please select Quantity before adding items.

生物活性	Glycochenodeoxycholic acid-d7 (Chenodeoxycholylglycine-d7) sodium is the deuterium labeled Glycochenodeoxycholic acid (sodium salt). Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	478.65
Formula	C₂₆H₃₅D₇NNaO₅
中文名称	甘氨鹅脱氧胆酸钠 d7 (钠盐)
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [3]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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Glycochenodeoxycholic acid-d4(Synonyms: Chenodeoxycholylglycine-d4)

发表于2023年12月16日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid-d4 (Synonyms: Chenodeoxycholylglycine-d4)

Glycochenodeoxycholic acid-d4 (Chenodeoxycholylglycine-d4) 是 Glycochenodeoxycholic acid 的氘代物。Glycochenodeoxycholic acid (Chenodeoxycholylglycine) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐。它起到洗涤剂的作用，可溶解脂肪吸收，并本身被吸收。Glycochenodeoxycholic acid (Chenodeoxycholylglycine) 诱导肝细胞凋亡。

Glycochenodeoxycholic acid-d4 Chemical Structure

CAS No. : 1201918-16-2

规格	价格	是否有货
1 mg	￥1500	询问价格 & 货期
5 mg	￥4500	询问价格 & 货期
10 mg	￥7800	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	Glycochenodeoxycholic acid-d4 (Chenodeoxycholylglycine-d4) is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	453.65
Formula	C₂₆H₃₉D₄NO₅
CAS 号	1201918-16-2
中文名称	甘氨鹅脱氧胆酸 d4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [3]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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Glycochenodeoxycholic acid-d4(Synonyms: Chenodeoxycholylglycine-d4)

发表于2023年12月16日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid-d4 (Synonyms: Chenodeoxycholylglycine-d4)

Glycochenodeoxycholic acid-d4 Chemical Structure

CAS No. : 1201918-16-2

规格	价格	是否有货
1 mg	￥1500	询问价格 & 货期
5 mg	￥4500	询问价格 & 货期
10 mg	￥7800	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	Glycochenodeoxycholic acid-d4 (Chenodeoxycholylglycine-d4) is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	453.65
Formula	C₂₆H₃₉D₄NO₅
CAS 号	1201918-16-2
中文名称	甘氨鹅脱氧胆酸 d4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [3]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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Glycochenodeoxycholic acid-d4(Synonyms: Chenodeoxycholylglycine-d4)

发表于2023年12月16日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid-d4 (Synonyms: Chenodeoxycholylglycine-d4)

Glycochenodeoxycholic acid-d4 Chemical Structure

CAS No. : 1201918-16-2

规格	价格	是否有货
1 mg	￥1500	询问价格 & 货期
5 mg	￥4500	询问价格 & 货期
10 mg	￥7800	询问价格 & 货期

* Please select Quantity before adding items.

生物活性	Glycochenodeoxycholic acid-d4 (Chenodeoxycholylglycine-d4) is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	453.65
Formula	C₂₆H₃₉D₄NO₅
CAS 号	1201918-16-2
中文名称	甘氨鹅脱氧胆酸 d4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [3]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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Glycochenodeoxycholic acid sodium salt(Synonyms: 甘氨鹅脱氧胆酸钠; Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate)

发表于2023年9月15日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid sodium salt (Synonyms: 甘氨鹅脱氧胆酸钠; Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate) 纯度: ≥98.0%

Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐。它起到洗涤剂的作用，可溶解脂肪吸收，并本身被吸收。Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) 可诱导肝细胞凋亡。

Glycochenodeoxycholic acid sodium salt Chemical Structure

CAS No. : 16564-43-5

规格	价格	是否有货
Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in DMSO	￥550	In-stock
100 mg	￥500	In-stock
200 mg		询价
500 mg		询价

* Please select Quantity before adding items.

Glycochenodeoxycholic acid sodium salt 相关产品

•相关化合物库:

Natural Product Library Plus
Bioactive Compound Library Plus
Apoptosis Compound Library
Metabolism/Protease Compound Library
Natural Product Library
Anti-Cancer Compound Library
Terpenoids Library
Gut Microbial Metabolite Library
Microbial Metabolite Library
Food-Sourced Compound Library

生物活性

Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis^[1]^[2].

分子量

471.61

Formula

C₂₆H₄₂NNaO₅

CAS 号

16564-43-5

中文名称

甘氨鹅脱氧胆酸钠

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

DMSO : 250 mg/mL (530.10 mM; Need ultrasonic)

H₂O : ≥ 100 mg/mL (212.04 mM)

* “≥” means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.1204 mL	10.6020 mL	21.2040 mL
5 mM	0.4241 mL	2.1204 mL	4.2408 mL
10 mM	0.2120 mL	1.0602 mL	2.1204 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： PBS

Solubility: 100 mg/mL (212.04 mM); Clear solution; Need ultrasonic
2.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.08 mg/mL (4.41 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (4.41 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
3.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.08 mg/mL (4.41 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (4.41 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
4.

请依序添加每种溶剂： 10% DMSO 90% corn oil

Solubility: ≥ 2.08 mg/mL (4.41 mM); Clear solution

此方案可获得 ≥ 2.08 mg/mL (4.41 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 20.8 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在上海金畔生物科技有限公司网站选购。

参考文献

[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30.

[2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Glycochenodeoxycholic acid(Synonyms: 甘氨鹅脱氧胆酸; Chenodeoxycholylglycine)

发表于2023年8月16日由上海金畔生物科技有限公司

Glycochenodeoxycholic acid (Synonyms: 甘氨鹅脱氧胆酸; Chenodeoxycholylglycine) 纯度: ≥98.0%

Glycochenodeoxycholic acid (Chenodeoxycholylglycine) 是一种从脱氧鹅胆酸和甘氨酸在肝脏中形成的胆汁盐。它起到洗涤剂的作用，可溶解脂肪吸收，并本身被吸收。Glycochenodeoxycholic acid (Chenodeoxycholylglycine) 诱导肝细胞凋亡。

Glycochenodeoxycholic acid Chemical Structure

CAS No. : 640-79-9

规格	价格	是否有货
Free Sample (0.1-0.5 mg)		Apply now
10 mM * 1 mL in DMSO	￥550	In-stock
10 mg	￥500	In-stock
50 mg		询价
100 mg		询价

* Please select Quantity before adding items.

Glycochenodeoxycholic acid 相关产品

•相关化合物库:

Natural Product Library Plus
Bioactive Compound Library Plus
Apoptosis Compound Library
Metabolism/Protease Compound Library
Natural Product Library
Anti-Cancer Compound Library
Human Endogenous Metabolite Compound Library
Gut Microbial Metabolite Library
Microbial Metabolite Library
Food-Sourced Compound Library

生物活性

Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis^[1]^[2].

IC₅₀ & Target

Human Endogenous Metabolite

分子量

449.62

Formula

C₂₆H₄₃NO₅

CAS 号

640-79-9

中文名称

甘氨鹅脱氧胆酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 100 mg/mL (222.41 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.2241 mL	11.1205 mL	22.2410 mL
5 mM	0.4448 mL	2.2241 mL	4.4482 mL
10 mM	0.2224 mL	1.1121 mL	2.2241 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline

Solubility: ≥ 2.5 mg/mL (5.56 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (5.56 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。

将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)

Solubility: ≥ 2.5 mg/mL (5.56 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (5.56 mM，饱和度未知) 的澄清溶液。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。

将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil

Solubility: ≥ 2.5 mg/mL (5.56 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (5.56 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。

以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在上海金畔生物科技有限公司网站选购。

参考文献

[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30.

[2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

Animal Administration ^[3]	Rats: The freshly isolated hepatocytes are preincubated for 2 h at a density of 1× 10⁶ cells/mL in a mixture of William’s E medium supplement with 10% FBS. Isolated rat hepatocytes are incubated in William’s E medium with or without (used as a control) GCDCA (50, 100 and 300 μM), or TG (1, 2 and 5 μM) for 1-24 h^[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

Animal Administration
^[3]

Rats: The freshly isolated hepatocytes are preincubated for 2 h at a density of 1× 10⁶ cells/mL in a mixture of William’s E medium supplement with 10% FBS. Isolated rat hepatocytes are incubated in William’s E medium with or without (used as a control) GCDCA (50, 100 and 300 μM), or TG (1, 2 and 5 μM) for 1-24 h^[3].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30.

[2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27.

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标签归档：glycochenodeoxycholic

Glycochenodeoxycholic acid-d7 sodium(Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

Glycochenodeoxycholic acid-d7 sodium(Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

Glycochenodeoxycholic acid-d7 sodium(Synonyms: Chenodeoxycholylglycine-d7 sodium; Sodium glycochenodeoxycholate-d7)

Glycochenodeoxycholic acid-d4(Synonyms: Chenodeoxycholylglycine-d4)

Glycochenodeoxycholic acid-d4(Synonyms: Chenodeoxycholylglycine-d4)

Glycochenodeoxycholic acid-d4(Synonyms: Chenodeoxycholylglycine-d4)

Glycochenodeoxycholic acid sodium salt(Synonyms: 甘氨鹅脱氧胆酸钠; Chenodeoxycholylglycine sodium salt; Sodium glycochenodeoxycholate)

Glycochenodeoxycholic acid sodium salt 相关产品

•相关化合物库:

Glycochenodeoxycholic acid(Synonyms: 甘氨鹅脱氧胆酸; Chenodeoxycholylglycine)

Glycochenodeoxycholic acid 相关产品

•相关化合物库:

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