| 产品名称 | α-马来酰亚胺基-ω-羧基琥珀酰亚胺酯聚（乙二醇），PEG分子量5,000Da |
|---|---|
| 英文名称 | alpha-Maleinimido-omega-carboxysuccinimidyl ester poly(ethyleneglycol), PEG molecular weight 5,000 daltons |
| 运输条件 | 常规运输 |
| 储存温度 | 室温 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | α-马来酰亚胺基-ω-羧基琥珀酰亚胺酯聚（乙二醇），PEG分子量3,000Da |
|---|---|
| 英文名称 | alpha-Maleinimido-omega-carboxysuccinimidyl ester poly(ethyleneglycol), PEG molecular weight 3,000 daltons |
| 分子量 | 3000 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | α-马来酰亚胺基-ω-羧基琥珀酰亚胺酯聚（乙二醇），PEG分子量10,000Da |
|---|---|
| 英文名称 | alpha-Maleinimido-omega-carboxysuccinimidyl ester poly(ethyleneglycol), PEG molecular weight 10,000 daltons |
| 分子量 | 10000 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | 炔-PEG₄-马来酰亚胺 |
|---|---|
| 英文名称 | Tris Buffered Saline with Tween 20: 500 ml of 10X |
| 别名 | 10X TBST |
| 英文别名 | 10X TBST |
| 运输条件 | 冰袋运输 |
炔基-PEG 4-马来酰亚胺是一种杂双功能交联剂，能够使含叠氮化物的化合物或生物分子与巯基连接。马来酰亚胺基团将优先与硫醇反应形成共价加合物，并且末端炔烃将通过铜催化的1，3-偶极环加成点击化学与叠氮化物反应。亲水性PEG间隔基增加了该试剂的水溶性，可轻松修饰含有半胱氨酸的生物分子，例如带有末端炔基的抗体，蛋白质和肽。PEG间隔基还通过增加亲水性来减少溶液中存储的修饰蛋白的聚集。
Tris Buffered Saline with Tween 20: 500 ml of 10X is a high-quality 10X concentrate for dilution to a 1X working solution commonly used as a wash solution for western blot membranes and microtiter plate wells in ELISA assays. Tris Buffered Saline with Tween 20 (TBST) is an optimal formulation of pH stabilizers, salts and detergents designed to effectively remove excess material from the microtiter plate wells without disrupting the ELISA binding reaction. By maintaining the proper buffering environment, unbound components can be washed away without suppressing antigen-antibody binding interactions, thereby reducing nonspecific background and increasing the specific signal.|Additional sizes and formats available:|Tris Buffered Saline with Tween 20: 1 L of 1X (sc-362187)|Tris Buffered Saline with Tween 20: 100 ml of 10X (sc-362309)|Tris Buffered Saline with Tween 20: 1 L of 10X (sc-24953)|Tris Buffered Saline with Tween 20: 1 L of 20X (sc-281695)|Tris Buffered Saline with Tween 20: 5 L of 20X (sc-362311)|Tris Buffered Saline with Tween 20: powder for 100 ml of 10X (sc-362190)|Tris Buffered Saline with Tween 20: powder for 500 ml of 10X (sc-362312)|Tris Buffered Saline with Tween 20: powder for 1 L of 10X (sc-362313)|Tris Buffered Saline with Tween 20: powder for 5 L of 10X (sc-362314)|Also available without Tween 20:|Tris Buffered Saline: 1 L of 1X (sc-362185)|Tris Buffered Saline: 1 L of 10X (sc-24951)|Tris Buffered Saline: 100 ml of 10X (sc-362303)|Tris Buffered Saline: 500 ml of 10X (sc-362304)|Tris Buffered Saline: 1 L of 20X (sc-362186)|Tris Buffered Saline: 5 L of 20X (sc-362305)|Tris Buffered Saline: powder for 100 ml of 10X (sc-362188)|Tris Buffered Saline: powder for 500 ml of 10X (sc-362306)|Tris Buffered Saline: powder for 1 L of 10X (sc-362307)|Tris Buffered Saline: powder for 5 L of 10X (sc-362308)
Dilute to a 1X solution with ddH20. Filter solution through a 0.22 μm filter into a sterile flask. Makes 5 L of 1X TBST buffer.Store the buffer solution at +4°C. Final concentration of Tween-20 (1X solution) = 0.05%.
Tris Buffered Saline with Tween 20: 500 ml of 10Xis a convenient prepared buffer for use in various applications
| 储存温度 | 2-8°C储存 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | NHS-PEG-NHS |
|---|---|
| 英文名称 | NHS-PEG-NHS |
| 别名 | N-羟基琥珀酰亚胺-PEG-N-羟基琥珀酰亚胺 |
| 英文别名 | Bis-succinimidyl PEG Ester |
| 规格或纯度 | MW 6000 Da |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 |
Generally, a 10 to 50-fold molar excess of NHS PEG over the amount of amine-containing material results in sufficient conjμgation. Materials Required:
Reaction Steps: Dissolve targeted materials in conjμgation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add NHS PEG stock solution to the targeted conjμgation materials with the final concentration keep at least 10 mg/mL. 10~50 molar excess of PEG NHS needed for optimal conjμgation; Allow mixture agitates at room temperature for 30~60 min at room temperature or 2 hours at 4 0C. Conjμgates can be purified either by size exclusion chromatography or dialysis. |
N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH2) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl carbonate (SC) functionalized mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.
N-hydroxylsuccinimide (NHS) functionalized polyethylene glycol (PEG-NHS) is an amino (-NH2) reactive PEG derivative that can be used to modify protein, peptide or any other surfaces with their available amino groups. NHS esters react with primary amine groups at pH 7~8.5 to form stable amide bonds.Compared to other PEG NHS ester derivatives, our succinimidyl carbonate (SC) functionalized mPEG-NHS offers superior reactivity and higher stability in aqueous solution. NHS esters react with deprotonated primary amines, therefore, the reaction requires neutral to basic pH values to proceed. Primary amines react with NHS esters by nucleophilic attack and NHS is released as a byproduct. Hydrolysis of the NHS-ester competes with the reaction in aqueous solution and increases with increasing pH.
| 敏感性 | 对湿度敏感 |
|---|---|
| 溶解性 | Soluble in regular aqeous solution as well as most organic solvents |
| 储存温度 | -20°C储存,充氩 |
| 品牌 | Jinpan |
| 产品名称 | 甲氧基聚乙二醇 5,000 乙酸 N-琥珀酰亚胺基酯 |
|---|---|
| 英文名称 | Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester |
| 别名 | 羧甲基-PEG 的琥珀酰亚胺酯 |
| 规格或纯度 | 80% |
| CAS编号 | 92451-01-9 |
|---|---|
| 储存温度 | 储存温度-20°C |
| MDL号 | MFCD01867746 |
| 品牌 | Jinpan |
| PubChem CID | 71312614 |
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Maleimide (Synonyms: 马来酰亚胺) 纯度: ≥98.0%
Maleimide 可用于制备用于癌症研究的抗体-药物偶联物 (ADC)。Maleimide 也可用于制备荧光探针，主要用于硫醇分析物的特异性检测。
Maleimide Chemical Structure
CAS No. : 541-59-3
| 规格 | 价格 | 是否有货 | 数量 |
|---|---|---|---|
| 10 mM * 1 mL in DMSO | ￥550 | In-stock | |
| 100 mg | ￥500 | In-stock | |
| 500 mg | ￥1500 | In-stock | |
| 1 g | 询价 | ||
| 5 g | 询价 |
* Please select Quantity before adding items.
| 生物活性 |
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2]. |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 分子量 |
97.07 |
||||||||||||||||
| Formula |
C4H3NO2 |
||||||||||||||||
| CAS 号 |
541-59-3 |
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| 中文名称 |
马来酰亚胺 |
||||||||||||||||
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
|
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| 溶解性数据 |
In Vitro:
DMSO : ≥ 100 mg/mL (1030.18 mM) H2O : 50 mg/mL (515.09 mM; Need ultrasonic) * “≥” means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂： ——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
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| 参考文献 |
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所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务
【编号】：VIP(XL)80078
【产品名称】：1,2-环己烷二甲酰亚胺对照品
【规格】：5mg；98%
【用途】：
| 产品名称 | Boc-L-丙氨酸-N-丁二酰亚胺酯 |
|---|---|
| 英文名称 | Boc-Ala-OSu |
| 别名 | Boc-L-丙氨酸丁二酰亚胺酯 |
| 英文别名 | N-Boc-L-alanine N-succinimidyl ester;Boc-L-alanine N-succinimidyl ester; Boc-L-Alanine N-hydroxysuccinimde ester; Succinimido (S)-2-[(tert-butoxycarbonyl)amino]propionate |
| 规格或纯度 | 98% |
| 运输条件 | 超低温冰袋运输 |
| 个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
|---|---|
| WGK | 3 |
| CAS编号 | 3392-05-0 |
|---|---|
| 敏感性 | 对湿度敏感 |
| 熔点 | 162-165°C |
| 储存温度 | -20°C储存,充氩 |
| MDL号 | MFCD00065974 |
| 密度 | 1.27 |
| 分子量 | 286.28 |
| 分子式 | C12H18N2O6 |
| EC号 | 222-229-7 |
| 品牌 | Jinpan |
| PubChem CID | 11011585 |
【编号】：VIP(XL)80796
【产品名称】：双(3-乙基-5-甲基-4-马来酰亚胺基苯基)甲烷对照品
【规格】：5mg；98%
【用途】：
| 产品名称 | α-甲氧基-ω-羧基琥珀酰亚胺酯PEG，PEG分子量5,000Da |
|---|---|
| 英文名称 | alpha-Methoxy-omega-carboxysuccinimidyl ester PEG, PEG molecular weight 5,000 daltons |
| 分子量 | 50000 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | α-甲氧基-ω-羧基琥珀酰亚胺酯PEG，PEG分子量2,000Da |
|---|---|
| 英文名称 | alpha-Methoxy-omega-carboxysuccinimidyl ester PEG, PEG molecular weight 2,000 daltons |
| 分子量 | 2000 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | N，N'-二琥珀酰亚胺草酸酯 |
|---|---|
| 英文名称 | N,N′-Disuccinimidyl oxalate |
| 英文别名 | N,N′-Disuccinimidyl oxalate; DSO; Di(N-succinimidyl) oxalate |
| 规格或纯度 | 85% |
| 运输条件 | 常规运输 |
用于制备N-受保护氨基酸的活性酯并以高收率制备受保护二肽的试剂（1-2）。
Reagent for preparing active esters of N-protected amino acids and for the preparation of protected dipeptides in good yields (1-2).
| CAS编号 | 57296-03-4 |
|---|---|
| 折光率 | n20D1.6 (Predicted) |
| 熔点 | 239° C (dec.) |
| 沸点 | ~427.9° C at 760 mmHg (Predicted) |
| 溶解性 | Soluble in water (react). |
| 储存温度 | 室温,干燥 |
| 密度 | ~1.7 g/cm3(Predicted) |
| 分子量 | 284.18 |
| 分子式 | C10H8N2O8 |
| 品牌 | Jinpan |
| Smiles | C1CC(=O)N(C1=O)OC(=O)C(=O)ON2C(=O)CCC2=O |
| PubChem CID | 5004084 |
| 产品名称 | ε-N-马来酰亚胺基己酸-（2-硝基-4-磺酸）-苯酯钠盐 |
|---|---|
| 英文名称 | epsilon-N-Maleimidocaproic acid-(2-nitro-4-sulfo)-phenyl ester sodium salt |
| 英文别名 | mal-sac-HNSA |
| 运输条件 | 冰袋运输 |
ε-N-马来酰亚胺基己酸-（2-硝基-4-磺酸）-苯基酯钠盐（mal-sac-HNSA）是常用的自由水溶性异双功能交联剂，用于偶联含巯基（半胱氨酸）的肽携带蛋白质。mal-sac-HNSA与氨基的反应可通过分光光度法进行监控，因为会伴随释放出1-羟基-2-硝基-4-苯磺酸的二价阴离子。
epsilon-N-Maleimidocaproic acid-(2-nitro-4-sulfo)-phenyl ester sodium salt (mal-sac-HNSA) is an often used freely water-soluble, heterobifunctional crosslinking reagent for conjugation of sulfhydryl (cysteine)-containing peptides to carrier proteins. The reaction of mal-sac-HNSA with amino groups can be monitored spectrophotometrically due to the concomitant release of the dianion of 1-hydroxy-2-nitro-4-benzenesulfonic acid.
| CAS编号 | 101554-76-1 |
|---|---|
| 折光率 | n20D~1.61 (Predicted) |
| 熔点 | 74° C |
| 储存温度 | 2-8°C储存 |
| 分子量 | 434.36 |
| 分子式 | C₁₆H₁₅N₂NaO₉S |
| 品牌 | Jinpan |
| Smiles | C1=CC(=C(C=C1S(=O)(=O)[O-])[N+](=O)[O-])OC(=O)CCCCCN2C(=O)C=CC2=O.[Na+] |
| PubChem CID | 13854811 |
| 产品名称 | N-α，N-α-双-Fmoc-L-胱氨酸双-N-羟基琥珀酰亚胺酯（二硫键） |
|---|---|
| 英文名称 | Nalpha,Nalpha-Bis-Fmoc-L-cystine bis-N-hydroxysuccinimide ester(Disulfide bond) |
| 运输条件 | 常规运输 |
Nalpha，Nalpha-Bis-Fmoc-L-胱氨酸双-N-羟基琥珀酰亚胺酯（二硫键）是受Fmoc保护的半胱氨酸衍生物，可能对蛋白质组学和固相肽合成技术有用。半胱氨酸是一种多功能氨基酸，涉及许多生物过程，包括二硫键的形成-二硫键是蛋白质结构的重要组成部分。该化合物可用作不寻常的氨基酸类似物，以帮助蛋白质结构和功能的去卷积。
Nalpha,Nalpha-Bis-Fmoc-L-cystine bis-N-hydroxysuccinimide ester(Disulfide bond) is an Fmoc protected cysteine derivative potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds – a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.
| CAS编号 | 112514-60-0 |
|---|---|
| 分子量 | 878.92 |
| 分子式 | C44H38N4O12S2 |
| 品牌 | Jinpan |
| PubChem CID | 91886225 |
| 产品名称 | N-羟基马来酰亚胺 |
|---|---|
| 英文名称 | N-Hydroxymaleimide |
| 英文别名 | N-Hydroxymaleamine; 1-Hydroxy-2,5-dihydro-1H-pyrrole-2,5-dione |
| 运输条件 | 常规运输 |
| CAS编号 | 4814-74-8 |
|---|---|
| 熔点 | 130-133° C (dec.) |
| 储存温度 | 室温,干燥 |
| 品牌 | Jinpan |
| Smiles | ON1C(=O)C=CC1=O |
| PubChem CID | 78535 |
| 产品名称 | [(叔丁氧羰基)氨基氧]乙酸N-琥珀酰亚胺酯 |
|---|---|
| 英文名称 | N-Succinimidyl [(tert-Butoxycarbonyl)aminooxy]acetate |
| 别名 | [(叔丁氧羰基)氨基氧]乙酸N-琥珀酰亚胺酯,(Boc-氨基氧)乙酸N-琥珀酰亚胺酯 |
| 英文别名 | [(tert-Butoxycarbonyl)aminooxy]acetic Acid N-Succinimidyl Ester；N-Succinimidyl (Boc-aminooxy)acetate；(Boc-aminooxy)acetic Acid N-Succinimidyl Ester |
| 规格或纯度 | 98% |
| 运输条件 | 超低温冰袋运输 |
| CAS编号 | 80366-85-4 |
|---|---|
| 敏感性 | 对光敏感、对潮湿敏感、对热敏感 |
| 熔点 | 114 °C |
| 储存温度 | 避光,-20°C储存,充氩 |
| Reaxys-RN | 7223602 |
| MDL号 | MFCD18382162 |
| 分子量 | 288.26 |
| 分子式 | C11H16N2O7 |
| 品牌 | Jinpan |
| PubChem CID | 12098210 |
| 产品名称 | [(叔丁氧羰基)氨基氧]乙酸N-琥珀酰亚胺酯 |
|---|---|
| 英文名称 | N-Succinimidyl [(tert-Butoxycarbonyl)aminooxy]acetate |
| 别名 | [(叔丁氧羰基)氨基氧]乙酸N-琥珀酰亚胺酯,(Boc-氨基氧)乙酸N-琥珀酰亚胺酯 |
| 英文别名 | [(tert-Butoxycarbonyl)aminooxy]acetic Acid N-Succinimidyl Ester；N-Succinimidyl (Boc-aminooxy)acetate；(Boc-aminooxy)acetic Acid N-Succinimidyl Ester |
| 规格或纯度 | 98% |
| 运输条件 | 超低温冰袋运输 |
| CAS编号 | 80366-85-4 |
|---|---|
| 敏感性 | 对光敏感、对潮湿敏感、对热敏感 |
| 熔点 | 114 °C |
| 储存温度 | 避光,-20°C储存,充氩 |
| Reaxys-RN | 7223602 |
| MDL号 | MFCD18382162 |
| 分子量 | 288.26 |
| 分子式 | C11H16N2O7 |
| 品牌 | Jinpan |
| PubChem CID | 12098210 |
