Doxorubicinone(Synonyms: Adriamycin aglycone; Adriamycinone)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Doxorubicinone (Synonyms: Adriamycin aglycone; Adriamycinone)

Doxorubicinone 是抗癌化疗药物阿霉素的代谢物。Doxorubicin 是一种有效的人 DNA 拓扑异构酶 I 和拓扑异构酶 II (topoisomerase l/II) 抑制剂,IC50 分别为 0.8 μM 和 2.67 μM。

Doxorubicinone(Synonyms: Adriamycin aglycone;  Adriamycinone)

Doxorubicinone Chemical Structure

CAS No. : 24385-10-2

规格 价格 是否有货
1 mg ¥4500 询问价格 & 货期
5 mg ¥13500 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

分子量

414.36

Formula

C21H18O9

CAS 号

24385-10-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Doxorubicinone(Synonyms: Adriamycin aglycone; Adriamycinone)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Doxorubicinone (Synonyms: Adriamycin aglycone; Adriamycinone)

Doxorubicinone 是抗癌化疗药物阿霉素的代谢物。Doxorubicin 是一种有效的人 DNA 拓扑异构酶 I 和拓扑异构酶 II (topoisomerase l/II) 抑制剂,IC50 分别为 0.8 μM 和 2.67 μM。

Doxorubicinone(Synonyms: Adriamycin aglycone;  Adriamycinone)

Doxorubicinone Chemical Structure

CAS No. : 24385-10-2

规格 价格 是否有货
1 mg ¥4500 询问价格 & 货期
5 mg ¥13500 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

分子量

414.36

Formula

C21H18O9

CAS 号

24385-10-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Doxorubicinone(Synonyms: Adriamycin aglycone; Adriamycinone)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Doxorubicinone (Synonyms: Adriamycin aglycone; Adriamycinone)

Doxorubicinone 是抗癌化疗药物阿霉素的代谢物。Doxorubicin 是一种有效的人 DNA 拓扑异构酶 I 和拓扑异构酶 II (topoisomerase l/II) 抑制剂,IC50 分别为 0.8 μM 和 2.67 μM。

Doxorubicinone(Synonyms: Adriamycin aglycone;  Adriamycinone)

Doxorubicinone Chemical Structure

CAS No. : 24385-10-2

规格 价格 是否有货
1 mg ¥4500 询问价格 & 货期
5 mg ¥13500 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

分子量

414.36

Formula

C21H18O9

CAS 号

24385-10-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Doxorubicinone-d3(Synonyms: Adriamycin aglycone-d3; Adriamycinone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Doxorubicinone-d3 (Synonyms: Adriamycin aglycone-d3; Adriamycinone-d3)

Doxorubicinone-d3 (Adriamycin aglycone-d3) 是 Doxorubicinone 的氘代物。Doxorubicinone 是抗癌化疗药物阿霉素的代谢物。Doxorubicin 是一种有效的人 DNA 拓扑异构酶 I 和拓扑异构酶 II (topoisomerase l/II) 抑制剂,IC50 分别为 0.8 μM 和 2.67 μM。

Doxorubicinone-d3(Synonyms: Adriamycin aglycone-d3;  Adriamycinone-d3)

Doxorubicinone-d3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Doxorubicinone-d3 (Adriamycin aglycone-d3) is the deuterium labeled Doxorubicinone. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

417.38

Formula

C21H15D3O9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Doxorubicinone-d3(Synonyms: Adriamycin aglycone-d3; Adriamycinone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Doxorubicinone-d3 (Synonyms: Adriamycin aglycone-d3; Adriamycinone-d3)

Doxorubicinone-d3 (Adriamycin aglycone-d3) 是 Doxorubicinone 的氘代物。Doxorubicinone 是抗癌化疗药物阿霉素的代谢物。Doxorubicin 是一种有效的人 DNA 拓扑异构酶 I 和拓扑异构酶 II (topoisomerase l/II) 抑制剂,IC50 分别为 0.8 μM 和 2.67 μM。

Doxorubicinone-d3(Synonyms: Adriamycin aglycone-d3;  Adriamycinone-d3)

Doxorubicinone-d3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Doxorubicinone-d3 (Adriamycin aglycone-d3) is the deuterium labeled Doxorubicinone. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

417.38

Formula

C21H15D3O9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Doxorubicinone-d3(Synonyms: Adriamycin aglycone-d3; Adriamycinone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Doxorubicinone-d3 (Synonyms: Adriamycin aglycone-d3; Adriamycinone-d3)

Doxorubicinone-d3 (Adriamycin aglycone-d3) 是 Doxorubicinone 的氘代物。Doxorubicinone 是抗癌化疗药物阿霉素的代谢物。Doxorubicin 是一种有效的人 DNA 拓扑异构酶 I 和拓扑异构酶 II (topoisomerase l/II) 抑制剂,IC50 分别为 0.8 μM 和 2.67 μM。

Doxorubicinone-d3(Synonyms: Adriamycin aglycone-d3;  Adriamycinone-d3)

Doxorubicinone-d3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Doxorubicinone-d3 (Adriamycin aglycone-d3) is the deuterium labeled Doxorubicinone. Doxorubicinone is a metabolite of an anti-cancer chemotherapy agent Doxorubicin[1]. Doxorubicin is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

417.38

Formula

C21H15D3O9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. M Joerger, et al. Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma. Cancer Chemother Pharmacol. 2005 May;55(5):488-96.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务