标签归档：ll

多肽定制Biotin-LL-37 编码

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名称 Biotin-LL-37
编码
别名 Biotin-LL-37
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Biotin-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-NH2
序列（三字母缩写） Biotin-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH2
基本描述
溶解度
分子量 0
化学式
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Biotin-LL-37 编码
Figures Biotin-LL-37 编码
Reference
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多肽定制Biotinyl-LL-37 amide 编码

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名称 Biotinyl-LL-37 amide
编码
别名 Biotinyl-LL-37 amide
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Biotinyl-LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES-NH2
序列（三字母缩写） Biotinyl-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-NH2?(trifluoroacetate salt)
基本描述 The peptide IRRP1 is derived from a consensus IFN-alpha sequence and corresponds to a putative receptor recognition domain of IFN-alpha. The binding capacity of cells for IFN-alphas was increased in the presence of IRRP1. Increased receptor occupancy resulted in increased phosphorylation-activation of the transcription factor ISGF3 and enhanced antiviral activity.
溶解度
分子量 4718.64
化学式 C215H355N63O54S1
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Biotinyl-LL-37 amide 编码
Figures Biotinyl-LL-37 amide 编码
Reference
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多肽定制Biotinyl-LL-37 amide 编码

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名称 Biotinyl-LL-37 amide
编码
别名 Biotinyl-LL-37 amide
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） FITC-betaAla-EIWIAQELR-S5-IGD-S5-FNAYYA (S5 & S5 need get stapled bond)
序列（三字母缩写） FITC-betaAla-Glu-Ile-Trp-Ile-Ala-Gln-Glu-Leu-Arg-S5-Ile-Gly-Asp-S5-Phe-Asn-Ala-Tyr-Tyr-Ala
基本描述 Cyclic MSH analog that is a potent full agonist of the melanocortin-3 and melanocortin-4 receptors (MC3-R and MC4-R). MTII is a useful tool in the study of the agouti obesity syndrome and the role of melanocortinergic neurons in feeding.
溶解度
分子量 4718.64
化学式 C215H355N63O54S
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Biotinyl-LL-37 amide 编码
Figures Biotinyl-LL-37 amide 编码
Reference
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多肽定制Cys-LL-37 编码

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名称 Cys-LL-37
编码
别名 Cys-LL-37
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） CLLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
序列（三字母缩写） H-Cys-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH (trifluoroacetate salt)
基本描述 Like ω-conotoxin GVIA, this Conus magus peptide inhibits presynaptic Ca2+ channels. However, ω-conotoxin MVIIC clearly inhibits additional Ca2+ channel subtypes in the mammalian central nervous system.This Conus magus peptide inhibits multiple types of channels including N- and P-channels.
溶解度
分子量 4596.47
化学式 C208H345N61O54S1
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Cys-LL-37 编码
Figures Cys-LL-37 编码
Reference Schmidtchen A, Frick IM, Andersson E, Tapper H, Bj?rck L. 2002. Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37. Mol Microbiol. 2002 46(1):157-168.
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多肽定制LL-37 编码 [154947-66-7]

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名称 LL-37
编码 [154947-66-7]
别名 LL-37
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
序列（三字母缩写） H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH (trifluoroacetate salt)
基本描述 LL-37 amide is an antimicrobial peptide with angiogenic activity.
溶解度
分子量 4493.33
化学式 C205H340N60O53
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents LL-37 编码 [154947-66-7]
Figures LL-37 编码 [154947-66-7]
Reference Z.Oren et al., Biochem. J., 341, 501 (1999) R.Koczulla et al., J. Clin. Invest., 111, 1665 (2003) R.Shaykhiev et al., Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L842 (2005) J.D.Heilborn et al., Int. J. Cancer, 114, 713 (2005) G.H. Gudmundsson et al.,Eur. J. Biochem., 238, 325 (1996) R. Bals et al., Cell. Mol. Life Sci., 60, 711 (2003) M. Zanetti, J. Leukoc. Biol., 75, 39 (2004) P.T. Liu et al., Science, 311, 770 (2006) R. Lande et al., Nature, 449, 564 (2007) P.Y. Ong et al., New Engl. J. Med., 347, 1151 (2002) D.W. Hoskin et al., Biochim. Biophys. Acta, 1778, 357 (2008) Y.P. Lai et al., Trends Immunol., 30, 131 (2009) M.F. Burton et al., Nat. Prod. Rep., 26, 1572 (2009)
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多肽定制LL-37 FK-13 编码 [717919-68-1]

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名称 LL-37 FK-13
编码 [717919-68-1]
别名 LL-37 FK-13
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） FKRIVQRIKDFLR
序列（三字母缩写） H-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-OH (trifluoroacetate salt)
基本描述 This peptide is the fragment of Histone H2B (1-22). It is acetylated at lysine 12 with a C-terminal GG linker followed by a biotinylated lysine. The histone H2B with acetylated at lysine 12 is a target for autoantibodies in systemic lupus erythematosus when it is apoptosis-induced.
溶解度
分子量 1719.11
化学式 C80H135N25O17
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents LL-37 FK-13 编码 [717919-68-1]
Figures LL-37 FK-13 编码 [717919-68-1]
Reference A.Sol et al., RCS Adv., 5, 9361 (2015) G.Wang et al., Antimicrob. Agents Chemother., 52, 3438 (2008)
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多肽定制LL-37 pentamide 编码

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上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 LL-37 pentamide
编码
别名 LL-37 pentamide
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） LLGNFFRKSKQKIGKQFKRIVQRIKNFFRNLVPRTQS
序列（三字母缩写） Leu-Leu-Gly-Asn-Phe-Phe-Arg-Lys-Ser-Lys-Gln-Lys-Ile-Gly-Lys-Gln-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asn-Phe-Phe-Arg-Asn-Leu-Val-Pro-Arg-Thr-Gln-Ser
基本描述
溶解度
分子量 4522.46
化学式 C208H343N65O48
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents LL-37 pentamide 编码
Figures LL-37 pentamide 编码
Reference
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多肽定制LL-37, Antimicrobial Peptide, human 编码 [597562-32-8]

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名称 LL-37, Antimicrobial Peptide, human
编码 [597562-32-8]
别名 LL-37, Antimicrobial Peptide, human
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
序列（三字母缩写） Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
基本描述
溶解度
分子量 4493.37
化学式 C205H340N60O53
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents LL-37, Antimicrobial Peptide, human 编码 [597562-32-8]
Figures LL-37, Antimicrobial Peptide, human 编码 [597562-32-8]
Reference
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多肽定制LL-37, reverse sequence 编码

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名称 LL-37, reverse sequence
编码
别名 LL-37, reverse sequence
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） SETRPVLNRLFDKIRQVIRKFEKGIKEKSKRFFDGLL
序列（三字母缩写） Ser-Glu-Thr-Arg-Pro-Val-Leu-Asn-Arg-Leu-Phe-Asp-Lys-Ile-Arg-Gln-Val-Ile-Arg-Lys-Phe-Glu-Lys-Gly-Ile-Lys-Glu-Lys-Ser-Lys-Arg-Phe-Phe-Asp-Gly-Leu-Leu
基本描述
溶解度
分子量 4493.37
化学式 C205H340N60O53
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents LL-37, reverse sequence 编码
Figures LL-37, reverse sequence 编码
Reference
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多肽定制LL-37-Cys 编码

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名称 LL-37-Cys
编码
别名 LL-37-Cys
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） LLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTESC
序列（三字母缩写） H-Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-Cys-OH (trifluoroacetate salt)
基本描述 This peptide is the fragment of Histone H2B (108-125) with a N-terminal biotinylated lysine.
溶解度
分子量 4596.47
化学式 C208H345N61O54S1
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents LL-37-Cys 编码
Figures LL-37-Cys 编码
Reference
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PR5-LL-CM01

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PR5-LL-CM01 

PR5-LL-CM01 是一种有效的 (PRMT5) 抑制剂 (IC50= 7.5 μM)。PR5-LL-CM01 具有抗肿瘤活性。

PR5-LL-CM01

PR5-LL-CM01 Chemical Structure

CAS No. : 1005307-86-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50= 7.5 μM). Anti-tumor activies[1].

体外研究
(In Vitro)

PR5-LL-CM01 has a range of IC50 at 2-4 μM in PDAC cells (PANC1, MiaPaCa2 and AsPC1, and a range of IC50 at 10-11 μM in CRC cells (HT29, HCT116 and DLD1). PR5-LL-CM01 has higher efficacy to specifically inhibit cancer cells and demonstrated low toxicity in normal cells. PR5-LL-CM01 strongly inhibited colony forming ability in both PANC1 and HT29 cells[1].
PR5-LL-CM01 inhibits NF-κB activation and its target gene expression in PDAC and CRC cells[1].
PR5-LL-CM01 (0-15 μM) dramatically decreases TNFα and IL8 expression in both PANC1 and HT29 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

PR5-LL-CM01 (20mg/kg; i.p.; 3 times per week) displays significant anti-tumor effect[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks old Male NSG mice (bearing PANC1 or HT29 cells)[1]
Dosage: 20 mg/kg (drug stock dissolved in 1:1 Cremophor:ethanol solution)
Administration: Intraperitoneally 3 times per week; 32 days (PANC1 model); 10 days (HT29 model)
Result: Led to significant tumor inhibition in both PANC1 and HT29 xenografted mice. Did not visibly affect the mice body weight.

分子量

401.51

Formula

C23H27N7
CAS 号

1005307-86-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Prabhu L, et al. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. 2017;8(25):39963-39977.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

PR5-LL-CM01

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PR5-LL-CM01 

PR5-LL-CM01 是一种有效的 (PRMT5) 抑制剂 (IC50= 7.5 μM)。PR5-LL-CM01 具有抗肿瘤活性。

PR5-LL-CM01

PR5-LL-CM01 Chemical Structure

CAS No. : 1005307-86-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50= 7.5 μM). Anti-tumor activies[1].

体外研究
(In Vitro)

PR5-LL-CM01 has a range of IC50 at 2-4 μM in PDAC cells (PANC1, MiaPaCa2 and AsPC1, and a range of IC50 at 10-11 μM in CRC cells (HT29, HCT116 and DLD1). PR5-LL-CM01 has higher efficacy to specifically inhibit cancer cells and demonstrated low toxicity in normal cells. PR5-LL-CM01 strongly inhibited colony forming ability in both PANC1 and HT29 cells[1].
PR5-LL-CM01 inhibits NF-κB activation and its target gene expression in PDAC and CRC cells[1].
PR5-LL-CM01 (0-15 μM) dramatically decreases TNFα and IL8 expression in both PANC1 and HT29 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

PR5-LL-CM01 (20mg/kg; i.p.; 3 times per week) displays significant anti-tumor effect[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks old Male NSG mice (bearing PANC1 or HT29 cells)[1]
Dosage: 20 mg/kg (drug stock dissolved in 1:1 Cremophor:ethanol solution)
Administration: Intraperitoneally 3 times per week; 32 days (PANC1 model); 10 days (HT29 model)
Result: Led to significant tumor inhibition in both PANC1 and HT29 xenografted mice. Did not visibly affect the mice body weight.

分子量

401.51

Formula

C23H27N7
CAS 号

1005307-86-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Prabhu L, et al. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. 2017;8(25):39963-39977.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

PR5-LL-CM01

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PR5-LL-CM01 

PR5-LL-CM01 是一种有效的 (PRMT5) 抑制剂 (IC50= 7.5 μM)。PR5-LL-CM01 具有抗肿瘤活性。

PR5-LL-CM01

PR5-LL-CM01 Chemical Structure

CAS No. : 1005307-86-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50= 7.5 μM). Anti-tumor activies[1].

体外研究
(In Vitro)

PR5-LL-CM01 has a range of IC50 at 2-4 μM in PDAC cells (PANC1, MiaPaCa2 and AsPC1, and a range of IC50 at 10-11 μM in CRC cells (HT29, HCT116 and DLD1). PR5-LL-CM01 has higher efficacy to specifically inhibit cancer cells and demonstrated low toxicity in normal cells. PR5-LL-CM01 strongly inhibited colony forming ability in both PANC1 and HT29 cells[1].
PR5-LL-CM01 inhibits NF-κB activation and its target gene expression in PDAC and CRC cells[1].
PR5-LL-CM01 (0-15 μM) dramatically decreases TNFα and IL8 expression in both PANC1 and HT29 cells[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究
(In Vivo)

PR5-LL-CM01 (20mg/kg; i.p.; 3 times per week) displays significant anti-tumor effect[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-8 weeks old Male NSG mice (bearing PANC1 or HT29 cells)[1]
Dosage: 20 mg/kg (drug stock dissolved in 1:1 Cremophor:ethanol solution)
Administration: Intraperitoneally 3 times per week; 32 days (PANC1 model); 10 days (HT29 model)
Result: Led to significant tumor inhibition in both PANC1 and HT29 xenografted mice. Did not visibly affect the mice body weight.

分子量

401.51

Formula

C23H27N7
CAS 号

1005307-86-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Prabhu L, et al. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. 2017;8(25):39963-39977.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

LL-37（人）三氟乙酸盐

发表于由

LL-37（人）三氟乙酸盐

≥95% (HPLC)

有货

LL-37（人）三氟乙酸盐

品牌：Jinpan
LL-37 (human) trifluoroacetate salt

MSDS

质检证书(CoA)

相似产品

货号 (SKU) 包装规格 是否现货 价格 数量
L463721-1mg 1mg 期货 LL-37（人）三氟乙酸盐  

基本信息

产品名称 LL-37（人）三氟乙酸盐
英文名称 LL-37 (human) trifluoroacetate salt
规格或纯度 ≥95% (HPLC)
运输条件 超低温冰袋运输

一般描述

Description

Chemical structure: peptideLL-37 is used to study host defense mechanisms.

Description

Chemical structure: peptideLL-37 is used to study host defense mechanisms.

相关属性

溶解性  H2O：1mg/mL，透明，无色
储存温度 -20°C储存
品牌 Jinpan