| 产品名称 | 甲氧苄氨嘧啶现成溶液 |
|---|---|
| 英文名称 | Trimethoprim Ready Made Solution |
| 英文别名 | Trimethoprim Ready Made Solution |
| 规格或纯度 | 25mg/mL in DMSO |
| 运输条件 | 超低温冰袋运输 |
Description
Trimethoprim is used at a final concentration of ~4μg/mL for antibacterial activty.
| 储存温度 | -20°C储存 |
|---|---|
| 品牌 | Jinpan |
| 产品名称 | 盐霉素，现成溶液 |
|---|---|
| 英文名称 | Salinomycin, Ready Made Solution |
| 英文别名 | Antibiotic 61477, Coxxistac |
| 规格或纯度 | 来自白色链霉菌,≥98%（HPLC） |
| 运输条件 | 超低温冰袋运输 |
Description
Chemical structure: polyetherSalinomycin, Ready Made Solution has been used as an inhibitor of endocytosis in primary pancreatic tumor cells. It has also been used in sequential treatment of cancer cells to study resistance.
Preparation instructions
Form
The product is supplied as a 2 mg/mL (2.66 mM) solution in DMSO, 0.2 μm-filtered.
Principle
| 溶解性 | DMSO：可溶；H2O：不溶；醇类：可溶；四氯化碳：可溶；氯仿：可溶；醚和酯：可溶；己烷：可溶 |
|---|---|
| 储存温度 | -20°C储存 |
| MDL号 | MFCD25541652 |
| 品牌 | Jinpan |
| 产品名称 | 格尔德霉素现成溶液 |
|---|---|
| 英文名称 | Geldanamycin Ready Made Solution |
| 英文别名 | 2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9,13-dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-, 9-carbamate (8CI) |
| 规格或纯度 | 1mg/mL,来自吸水链霉菌 |
Description
Chemical structure: benzenoidGeldanamycin Ready-Made Solution has been used as a heat shock protein 90 (Hsp90) inhibitor to pre-treat proteosome holo-enzyme during proteasome assay to study the role of proteasome on fibril fragmentation.
| CAS编号 | 30562-34-6 |
|---|---|
| 熔点 | 255°C |
| 储存温度 | 避光 |
| Reaxys-RN | 6835113 |
| RTECS | LX8920000 |
| 分子量 | 560.64 |
| 分子式 | C29H40N2O9 |
| 品牌 | Jinpan |
| Smiles | ;CO[C@@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)C(=CC=C[C@H](OC)[C@H](OC(=O)N)C(=C[C@@H](C)[C@H]1O)C)C)C2=O;CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)C(=CC=C[C@H](OC)[C@@H](OC(=O)N)C(=C[C@H](C)[C@@H]1O)C)C)C2=O;CO[C@H]1C[C@H](C)CC2=C(OC)C(=O)C=C(NC(=O)C(=CC=C[C |
| PubChem CID | 5288382 |
| 产品名称 | 复方新诺明，现成溶液 |
|---|---|
| 英文名称 | Cotrimoxazole, Ready Made Solution |
| 英文别名 | Trimethoprim-Sulfamethoxazole, TMP-SMX |
| 规格或纯度 | 100mg/mL in DMSO |
| 运输条件 | 超低温冰袋运输 |
| 生化机理 | 复方新诺明是甲氧苄啶和磺胺甲恶唑的组合，可通过阻止核苷酸的生物合成来干扰叶酸在细菌细胞中的细胞代谢。甲氧苄啶与二氢叶酸还原酶（DHFR）结合，从而抑制二氢叶酸（DHF）还原为四氢叶酸（THF），从而产生抗菌作用。新诺明通过阻止对氨基苯甲酸向辅酶二氢叶酸的转化来干扰敏感微生物中核酸的合成。这些作用的最终结果是抑制胸腺嘧啶核苷的合成，从而阻止细菌 DNA 的合成。 |
应用
复方新诺明已被用作抗菌剂。
适用性
原理
制备说明
使用甲氧苄啶：磺胺甲恶唑的 1：5 混合物制备
外形
Description
Cotrimoxazole has been used as an antimicrobial agent.
| CAS编号 | 8064-90-2 |
|---|---|
| 储存温度 | -20°C储存 |
| 分子量 | 543.6 |
| 分子式 | C24H29N7O6S |
| 品牌 | Jinpan |
| 备注 | 保存于密闭容器内，置于干燥通风处。 |
| PubChem CID | 358641 |
| 产品名称 | Aphi二colin，现成的溶液 |
|---|---|
| 英文名称 | Aphidicolin, Ready Made Solution |
| 英文别名 | ICI 69653, NSC-234714 |
| 规格或纯度 | 来自球形黑孢菌 |
| 运输条件 | 超低温冰袋运输 |
Description
Aphidicolin is a tetracyclic diterpene with antiviral and antimitotic properties used for cell cycle synchronization in various cell lines.Aphidicolin, fromNigrospora sphaerica, was used for cell cycle synchronization of tobacco BY-2 cells. It is used to block the entry of cells into S-phase.
Preparation instructions
Form
Aphidicolin Ready Made Solution supplied as a 1 mg/ml solution in DMSO.
Principle
Description
Aphidicolin is a tetracyclic diterpene with antiviral and antimitotic properties used for cell cycle synchronization in various cell lines.Aphidicolin, fromNigrospora sphaerica, was used for cell cycle synchronization of tobacco BY-2 cells. It is used to block the entry of cells into S-phase.
Preparation instructions
Form
Aphidicolin Ready Made Solution supplied as a 1 mg/ml solution in DMSO.
Principle
| CAS编号 | 38966-21-1 |
|---|---|
| 溶解性 | H2O：可混溶（完全） |
| 储存温度 | -20°C储存 |
| RTECS | PB9185000 |
| MDL号 | MFCD00083214 |
| 分子量 | 338.48 |
| 分子式 | C20H34O4 |
| 品牌 | Jinpan |
| PubChem CID | 457964 |
| 产品名称 | 克拉霉素，现成溶液 |
|---|---|
| 英文名称 | Clarithromycin, Ready Made Solution |
| 别名 | 6-O-methyl erythromycin |
| 英文别名 | 6-O-methyl erythromycin |
| 规格或纯度 | 50 mg/mL in DMSO |
| 生化机理 | Macrolides, such as clarithromycin, prevent protein synthesis in bacteria, by binding to 50S ribosomal subunit. It also binds to other ribosomal proteins, and prevents the translocation of pepti-dyl-tRNA. In patients with refractory asthma, it is capable of regulating the levels of interleukin-8 (IL-8), and neutrophil accumulation and activation in lungs. Thus, it might be used as an additional therapy in asthma to reduce noneosinophilic airway inflammation. |
General Description
Clarithromycin is a macrolide antibiotic, which has both antibacterial and anti-inflammatory actions. It is a semi-synthetic 14-membered derivative of erythromycin A, which is resistant to degradation under acidic conditions.
Application
Clarithromycin may be used for- the study of the effects of clarithromycin on rate-dependent changes in QT, T p-e and proarrhythmic events performed on arterially perfused rabbit left ventricular wedge preparations the culture of parasites expressing GFP (green fluorescence protein) targeted to the apicoplast, to be further used for microscopy-based assays the study of the synergism of NAB741 with clarithromycin in microtiter plates.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Combustible liquids
General Description
Clarithromycin is a macrolide antibiotic, which has both antibacterial and anti-inflammatory actions. It is a semi-synthetic 14-membered derivative of erythromycin A, which is resistant to degradation under acidic conditions.
Application
Clarithromycin may be used for- the study of the effects of clarithromycin on rate-dependent changes in QT, T p-e and proarrhythmic events performed on arterially perfused rabbit left ventricular wedge preparations the culture of parasites expressing GFP (green fluorescence protein) targeted to the apicoplast, to be further used for microscopy-based assays the study of the synergism of NAB741 with clarithromycin in microtiter plates.
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Storage class (TRGS 510): Combustible liquids
| CAS编号 | 81103-11-9 |
|---|---|
| 比旋光度 | -92°C |
| 熔点 | 225°C |
| 储存温度 | 干燥 |
| RTECS | KF4997000 |
| 分子量 | 747.95 |
| 分子式 | C38H69NO13 |
| 品牌 | Jinpan |
| PubChem CID | 84029 |
| 产品名称 | 茴香霉素，来自灰色链霉菌的现成溶液 |
|---|---|
| 英文名称 | Anisomycin, Ready Made Solution from Streptomyces griseolus |
| 英文别名 | Flagecidin, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate, (2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate |
| 规格或纯度 | 10mg/mL in DMSO |
| 运输条件 | 超低温冰袋运输 |
| CAS编号 | 22862-76-6 |
|---|---|
| 比旋光度 | -30° (C=1,MeOH) |
| 熔点 | 144 °C |
| 储存温度 | -20°C储存 |
| RTECS | BZ9800000 |
| 分子量 | 265.3 |
| 分子式 | C14H19NO4 |
| EC号 | 245-269-7 |
| 品牌 | Jinpan |
| PubChem CID | 253602 |
