标签归档：catalase

Catalase(Synonyms: 过氧化氢酶)

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Catalase (Synonyms: 过氧化氢酶)

Catalase 是重要的抗氧化酶,在清除 ROS。在维持氧化还原状态的平衡方面发挥着重要作用。Catalase 与肿瘤的发生,发展关系密切。有潜力用于肿瘤的预防研究。

Catalase(Synonyms: 过氧化氢酶)

Catalase Chemical Structure

CAS No. : 9001-05-2

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Catalase 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus

生物活性

Catalase is a key enzyme in the metabolism of H2O2 and reactive oxygen species (ROS), and its expression and localization is markedly altered in tumors[1]. Free oxygen radical scavenger.

体外研究
(In Vitro)

Catalase, the enzyme that metabolizes H2O2 but also reacts with a multitude of other substrates. The active site of catalase contains an iron atom. Human catalase contains four identical subunits, each subunit containing four distinct domains and one prosthetic heme group. The four domains include: (1) a N-terminal arm which contains a distal histidine, an essential amino acid for the catalase reaction; (2) a β-barrel domain that contains eight β-barrels arranged in an antiparallel fashion with six α-helical insertions, conferring the hydrophobic core of the protein necessary for the tri-dimensional structure of the enzyme; (3) a connection domain which contains the tyrosine residue that binds the heme group; and finally (4) an α-helical domains, which is important for NADPH binding[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial

CAS 号

9001-05-2
中文名称

过氧化氢酶
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O : 33.33 mg/mL (Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)
参考文献

  • [1]. Glorieux C, et al. Catalase, a remarkable enzyme: targeting the oldest antioxidant enzyme to find a new cancer treatment approach. Biol Chem. 2017 Sep 26;398(10):1095-1108.

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Catalase, Fluorescein labeled Cat. No. CTS-FC-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, Fluorescein labeled

Cat. No. CTS-FC-1
Specification
Unit Size 2 mg
Price $385.00

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Description:

Fluorescein labeled catalase is one of Nanocs’ fluorescent catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. Fluorescein modified catalase is a green fluorescent catalase conjugates with excitation/emission wavelength around 495 nm/515 nm. These functionalized catalase conjugates were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 2~7 fluorescein dyes on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C. Desiccate. Protect from light.

Catalase, Rhodamine labeled Cat. No. CTS-RB-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, Rhodamine labeled

Cat. No. CTS-RB-1
Specification
Unit Size 2 mg
Price $385.00

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Description:

Rhodamine B labeled catalase is one of Nanocs’ fluorescent catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. Rhodamine B modified catalase is a red fluorescent catalase conjugates with excitation/emission wavelength around 544 nm/576 nm. All our functionalized catalase conjugates were purified by size exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 2~7 Rhodamine dyes on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C. Desiccate. Protect from light.

Catalase, Cy3 labeled Cat. No. CTS-S3-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, Cy3 labeled

Cat. No. CTS-S3-1
Specification
Unit Size 2 mg
Price $385.00

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Description:

Cy3 labeled catalase is one of Nanocs’ fluorescent catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. Cy3 modified catalase is a red fluorescent catalase conjugates with excitation/emission wavelength around 550 nm/570 nm. All our functionalized catalase conjugates were purified by size exclusion chromatography to ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 2~7 Cy3 dyes on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C. Desiccate. Protect from light.

Catalase, Cy5 labeled Cat. No. CTS-S5-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, Cy5 labeled

Cat. No. CTS-S5-1
Specification
Unit Size 2 mg
Price $385.00

Qty Add to Cart

Description:

Cy5 labeled catalase is one of Nanocs’ fluorescent catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. Cy5 modified catalase is a near IR fluorescent catalase conjugates with excitation/emission wavelength around 650 nm/670 nm. These functionalized catalase conjugates were purified by size exclusion chromatography to ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 2~7 Cy5 dyes on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C. Desiccate. Protect from light.

Catalase, Cy7 labeled Cat. No. CTS-S7-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, Cy7 labeled

Cat. No. CTS-S7-1
Specification
Unit Size 2 mg
Price $385.00

Qty Add to Cart

Description:

Cy7 labeled catalase is one of Nanocs’ fluorescent catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. Cy7 modified catalase is a near IR fluorescent catalase conjugates with excitation/emission wavelength around 743 nm/767 nm. All our functionalized catalase conjugates were purified by size exclusion chromatography to ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 2~7 Cy7 fluorophores on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C. Protect from light.

Catalase, Biotin labeled Cat. No. CTS-BN-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, Biotin labeled

Cat. No. CTS-BN-1
Specification
Unit Size 2 mg
Price $385.00

Qty Add to Cart

Description:

Biotin labeled catalase is one of Nanocs’ biotinylated catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. Biotin modified catalase is able to bind to avidin or streptavidin with high affinity. All our functionalized catalase conjugates were purified by size exclusion chromatography to ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 2~7 Biotins on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C.

Catalase, PEG labeled Cat. No. CTS-PEG-1 2 mg修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Catalase, PEG labeled

Cat. No. CTS-PEG-1
Specification
Unit Size 2 mg
Price $385.00

Qty Add to Cart

Description:

PEG labeled catalase is one of Nanocs’ pegylated catalase conjugates. Catalase is a common enzyme found in nearly all living organisms exposed to oxygen. It catalyzes the decomposition of hydrogen peroxide to water and oxygen. Catalase is a important enzyme in protetecting the cell from oxidative damage by reactive oxygen species. PEG modified catalase shows better stability with good reactivity. Nanocs provides a variety of chemically functionalized and bioconjugated catalase with different functionality. These functionalized catalase conjugates were purified by size exclusion chromatography to ensure adequate applications both in-vitro and in-vivo.

Specifications:

  • 20~50 PEG5000 on each catalase molecule.
  • Catalase conjugates provided either in water solution or dried powder;

Storage Conditions:

  • Store at 4 0C.