PROTAC CRABP-II Degrader-1

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PROTAC CRABP-II Degrader-1

PROTAC CRABP-II Degrader-1 是一种基于IAP 配体的、细胞视黄酸结合蛋白 (CRABP-II) 的降解剂。

PROTAC CRABP-II Degrader-1 Chemical Structure

CAS No. : 1225383-40-3

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生物活性	PROTAC CRABP-II Degrader-1 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on IAP ligand^[1].
IC₅₀ & Target	SNIPER, PROTAC^[1].
分子量	764.95
Formula	C₄₂H₆₀N₄O₉
CAS 号	1225383-40-3
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

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PROTAC CRABP-II Degrader-2

PROTAC CRABP-II Degrader-2

PROTAC CRABP-II Degrader-2 是一种基于 IAP 配体的、细胞视黄酸结合蛋白 (CRABP-II) 的降解剂。

PROTAC CRABP-II Degrader-2 Chemical Structure

CAS No. : 1225383-38-9

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生物活性	PROTAC CRABP-II Degrader-2 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on IAP ligand^[1].
IC₅₀ & Target	SNIPER, PROTAC^[1].
分子量	809.00
Formula	C₄₄H₆₄N₄O₁₀
CAS 号	1225383-38-9
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

PROTAC CRABP-II Degrader-3

PROTAC CRABP-II Degrader-3 是一种基于 IAP 配体的、细胞视黄酸结合蛋白 (CRABP-II) 的降解剂。

PROTAC CRABP-II Degrader-3 Chemical Structure

CAS No. : 1225383-41-4

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生物活性	PROTAC CRABP-II Degrader-3 is a potent cellular retinoic acid binding protein (CRABP-II) degrader based on IAP ligand^[1].
IC₅₀ & Target	SNIPER, PROTAC^[1].
分子量	853.05
Formula	C₄₆H₆₈N₄O₁₁
CAS 号	1225383-41-4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

ATRA-hydroxyimino (Synonyms: CRABP-II ligand 1)

ATRA-hydroxyimino (CRABP-II ligand 1) 是一种基于 Retinoic acid (ATRA) 的 moiety，可通过 linker 与 cIAP1 配体 (Bestatin) 结合从而形成 SNIPER 分子，可降解 IMR-32 细胞中 CRABP-II。

ATRA-hydroxyimino Chemical Structure

CAS No. : 135325-47-2

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生物活性	ATRA-hydroxyimino (CRABP-II ligand 1), the Retinoic acid (ATRA)-based moiety, binds to cIAP1 ligand (Bestatin) via a linker to form SNIPER to degrade CRABP-II in IMR-32 cells^[1].
IC₅₀ & Target	CRABP-II, PROTAC^[1].
分子量	329.43
Formula	C₂₀H₂₇NO₃
CAS 号	135325-47-2
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Scheepstra M, et al. Bivalent Ligands for Protein Degradation in Drug Discovery. Comput Struct Biotechnol J. 2019 Jan 25;17:160-176.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务