ar-Turmerone(Synonyms: (+)-ar-Turmerone)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ar-Turmerone (Synonyms: (+)-ar-Turmerone)

ar-Turmerone ((+)-ar-Turmerone) 是姜黄的主要生物活性成分,具有抗肿瘤和抗炎作用。在人类淋巴瘤 U937 细胞中,ar-turmerone 能激活凋亡蛋白。ar-Turmerone 对小鼠树突细胞具有正向调节作用,能诱导神经干细胞增殖,可用于神经疾病的研究。

ar-Turmerone(Synonyms: (+)-ar-Turmerone)

ar-Turmerone Chemical Structure

CAS No. : 532-65-0

规格 价格 是否有货
5 mg ¥4000 询问价格 & 货期
10 mg ¥6800 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

分子量

216.32

Formula

C15H20O

CAS 号

532-65-0

中文名称

芳姜黄酮

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.

    [2]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.

    [3]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.

    [4]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.

    [5]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

ar-Turmerone-d3(Synonyms: (+)-ar-Turmerone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ar-Turmerone-d3 (Synonyms: (+)-ar-Turmerone-d3)

ar-Turmerone-d3 ((+)-ar-Turmerone-d3) 是 ar-Turmerone 的氘代物。ar-Turmerone ((+)-ar-Turmerone) 是姜黄的主要生物活性成分,具有抗肿瘤和抗炎作用。在人类淋巴瘤 U937 细胞中,ar-turmerone 能激活凋亡蛋白。ar-Turmerone 对小鼠树突细胞具有正向调节作用,能诱导神经干细胞增殖,可用于神经疾病的研究[4]

ar-Turmerone-d3(Synonyms: (+)-ar-Turmerone-d3)

ar-Turmerone-d3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

ar-Turmerone-d3 ((+)-ar-Turmerone-d3) is the deuterium labeled ar-Turmerone. ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

219.34

Formula

C15H17D3O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.

    [3]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.

    [4]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.

    [5]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.

    [6]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

ar-Turmerone-d3(Synonyms: (+)-ar-Turmerone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ar-Turmerone-d3 (Synonyms: (+)-ar-Turmerone-d3)

ar-Turmerone-d3 ((+)-ar-Turmerone-d3) 是 ar-Turmerone 的氘代物。ar-Turmerone ((+)-ar-Turmerone) 是姜黄的主要生物活性成分,具有抗肿瘤和抗炎作用。在人类淋巴瘤 U937 细胞中,ar-turmerone 能激活凋亡蛋白。ar-Turmerone 对小鼠树突细胞具有正向调节作用,能诱导神经干细胞增殖,可用于神经疾病的研究[4]

ar-Turmerone-d3(Synonyms: (+)-ar-Turmerone-d3)

ar-Turmerone-d3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

ar-Turmerone-d3 ((+)-ar-Turmerone-d3) is the deuterium labeled ar-Turmerone. ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

219.34

Formula

C15H17D3O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.

    [3]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.

    [4]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.

    [5]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.

    [6]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

ar-Turmerone-d3(Synonyms: (+)-ar-Turmerone-d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

ar-Turmerone-d3 (Synonyms: (+)-ar-Turmerone-d3)

ar-Turmerone-d3 ((+)-ar-Turmerone-d3) 是 ar-Turmerone 的氘代物。ar-Turmerone ((+)-ar-Turmerone) 是姜黄的主要生物活性成分,具有抗肿瘤和抗炎作用。在人类淋巴瘤 U937 细胞中,ar-turmerone 能激活凋亡蛋白。ar-Turmerone 对小鼠树突细胞具有正向调节作用,能诱导神经干细胞增殖,可用于神经疾病的研究[4]

ar-Turmerone-d3(Synonyms: (+)-ar-Turmerone-d3)

ar-Turmerone-d3 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

ar-Turmerone-d3 ((+)-ar-Turmerone-d3) is the deuterium labeled ar-Turmerone. ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone activates apoptotic protein in human lymphoma U937 cells[3]. ar-Turmerone exerts positive modulation on murine DCs. ar-Turmerone induces NSC proliferation and constitutes a promising therapeutic agent for various neurologic disorders[4][5].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

219.34

Formula

C15H17D3O

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Liju VB, et al. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L. Indian J Pharmacol. 2011 Sep;43(5):526-31.

    [3]. Yue GG, et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. Food Chem Toxicol. 2010 Aug-Sep;48(8-9):2011-20.

    [4]. Lee Y, et al. Activation of apoptotic protein in U937 cells by a component of turmeric oil. BMB Rep. 2009 Feb 28;42(2):96-100.

    [5]. Yonggang T, et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR). Hum Vaccin Immunother. 2012 Oct;8(10):1416-24.

    [6]. Hucklenbroich J, et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo. Stem Cell Res Ther. 2014 Sep 26;5(4):100.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务