Heptadecanoic acid-d3(Synonyms: 十七烷酸 d3)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Heptadecanoic acid-d3 (Synonyms: 十七烷酸 d3)

Heptadecanoic acid-d3 是 Heptadecanoic acid 的氘代物。Heptadecanoic acid 是一种奇链饱和脂肪酸 (OCS-FA )。Heptadecanoic acid 与一些疾病有关,包括冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症。

Heptadecanoic acid-d3(Synonyms: 十七烷酸 d3)

Heptadecanoic acid-d3 Chemical Structure

CAS No. : 202528-95-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Heptadecanoic acid-d3 is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

273.47

Formula

C17H31D3O2

CAS 号

202528-95-8

中文名称

十七烷酸 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Changzhi Xu, et al. Heptadecanoic acid inhibits cell proliferation in PC‑9 non‑small‑cell lung cancer cells with acquired gefitinib resistancey. Oncol Rep. 2019 Jun;41(6):3499-3507.

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Heptadecanoic acid(Synonyms: 十七烷酸)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Heptadecanoic acid (Synonyms: 十七烷酸) 纯度: ≥97.0%

Heptadecanoic acid 是一种奇链饱和脂肪酸 (OCS-FA )。Heptadecanoic acid 与一些疾病有关,包括冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症。

Heptadecanoic acid(Synonyms: 十七烷酸)

Heptadecanoic acid Chemical Structure

CAS No. : 506-12-7

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ¥550 In-stock
100 mg ¥500 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Heptadecanoic acid 相关产品

相关化合物库:

  • Natural Product Library Plus
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  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Anti-Cancer Compound Library
  • Diabetes Related Compound Library
  • Lipid Compound Library
  • Anti-Cardiovascular Disease Compound Library
  • Traditional Chinese Medicine Monomer Library
  • Food-Sourced Compound Library

生物活性

Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].

分子量

270.45

Formula

C17H34O2

CAS 号

506-12-7

中文名称

十七烷酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 120 mg/mL (443.70 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.6975 mL 18.4877 mL 36.9754 mL
5 mM 0.7395 mL 3.6975 mL 7.3951 mL
10 mM 0.3698 mL 1.8488 mL 3.6975 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 3 mg/mL (11.09 mM); Suspended solution; Need ultrasonic

    此方案可获得 3 mg/mL (11.09 mM) 的均匀悬浊液,悬浊液可用于口服和腹腔注射。

    以 1 mL 工作液为例,取 100 μL 30.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 3 mg/mL (11.09 mM); Clear solution

    此方案可获得 ≥ 3 mg/mL (11.09 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 30.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 3 mg/mL (11.09 mM); Clear solution

    此方案可获得 ≥ 3 mg/mL (11.09 mM,饱和度未知) 的澄清溶液,此方案不适用于实验周期在半个月以上的实验。

    以 1 mL 工作液为例,取 100 μL 30.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中,混合均匀。

*以上所有助溶剂都可在 上海金畔生物科技有限公司 网站选购。
参考文献
  • [1]. Changzhi Xu, et al. Heptadecanoic acid inhibits cell proliferation in PC‑9 non‑small‑cell lung cancer cells with acquired gefitinib resistancey. Oncol Rep. 2019 Jun;41(6):3499-3507.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Heptadecanoic acid-d33(Synonyms: 十七烷酸 d33)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Heptadecanoic acid-d33 (Synonyms: 十七烷酸 d33)

Heptadecanoic-d33 acid是 Heptadecanoic acid 的氘代物。Heptadecanoic acid 是一种奇链饱和脂肪酸 (OCS-FA )。Heptadecanoic acid 与一些疾病有关,包括冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症。

Heptadecanoic acid-d33(Synonyms: 十七烷酸 d33)

Heptadecanoic acid-d33 Chemical Structure

CAS No. : 352431-41-5

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Heptadecanoic-d33 acid is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

303.65

Formula

C17HD33O2

CAS 号

352431-41-5

中文名称

十七烷酸 d33

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Heptadecanoic acid-d33(Synonyms: 十七烷酸 d33)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Heptadecanoic acid-d33 (Synonyms: 十七烷酸 d33)

Heptadecanoic-d33 acid是 Heptadecanoic acid 的氘代物。Heptadecanoic acid 是一种奇链饱和脂肪酸 (OCS-FA )。Heptadecanoic acid 与一些疾病有关,包括冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症。

Heptadecanoic acid-d33(Synonyms: 十七烷酸 d33)

Heptadecanoic acid-d33 Chemical Structure

CAS No. : 352431-41-5

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Heptadecanoic-d33 acid is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

303.65

Formula

C17HD33O2

CAS 号

352431-41-5

中文名称

十七烷酸 d33

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Heptadecanoic acid-d33(Synonyms: 十七烷酸 d33)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Heptadecanoic acid-d33 (Synonyms: 十七烷酸 d33)

Heptadecanoic-d33 acid是 Heptadecanoic acid 的氘代物。Heptadecanoic acid 是一种奇链饱和脂肪酸 (OCS-FA )。Heptadecanoic acid 与一些疾病有关,包括冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症。

Heptadecanoic acid-d33(Synonyms: 十七烷酸 d33)

Heptadecanoic acid-d33 Chemical Structure

CAS No. : 352431-41-5

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Heptadecanoic-d33 acid is the deuterium labeled Heptadecanoic acid. Heptadecanoic acid is an odd chain saturated fatty acid (OCS-FA). Heptadecanoic acid is associated with several diseases, including the incidence of coronary heart disease, prediabetes and type 2 diabetes as well as multiple sclerosis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

303.65

Formula

C17HD33O2

CAS 号

352431-41-5

中文名称

十七烷酸 d33

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务