标签归档：sulfo

sulfo-SPDB

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

sulfo-SPDB  纯度: ≥95.0%

sulfo-SPDB 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

sulfo-SPDB

sulfo-SPDB Chemical Structure

CAS No. : 1193111-39-5

规格 价格 是否有货 数量
5 mg ￥3500 In-stock
10 mg ￥5500 询价
25 mg ￥11000 询价
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

生物活性

sulfo-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

406.45

Formula

C13H14N2O7S3
CAS 号

1193111-39-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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Sulfo-SNPB

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo-SNPB 

Sulfo-SNPB 是一种用于制备抗体偶联药物 (ADC) 的可降解 linker 。

Sulfo-SNPB

Sulfo-SNPB Chemical Structure

CAS No. : 1193111-37-3

规格 是否有货
1 g 询价

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生物活性

Sulfo-SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

IC50 & Target[1]

Cleavable

 

分子量

451.45

Formula

C13H13N3O9S3
CAS 号

1193111-37-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Robert J. Lutz, et al. Methods for decreasing ocular toxicity of antibody drug conjugates. WO2012138749A1.

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NO2-SPP-sulfo-Me

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NO2-SPP-sulfo-Me 

NO2-SPP-sulfo-Me 是一种用于制备抗体偶联药物 (ADC) 的可降解 linker 。

NO2-SPP-sulfo-Me

NO2-SPP-sulfo-Me Chemical Structure

CAS No. : 890409-87-7

规格 价格 是否有货
100 mg ￥9200 询问价格 & 货期

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生物活性

NO2-SPP-sulfo-Me is a cleavable linker that is used for making antibody-drug conjugate (ADC)[1].

IC50 & Target[1]

Cleavable

 

分子量

463.51

Formula

C15H17N3O8S3
CAS 号

890409-87-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Robert J. Lutz, et al.Methods for decreasing ocular toxicity of antibody drug conjugates. WO2012138749A1.

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Sulfo-SIAB

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Sulfo-SIAB 

Sulfo-SIAB 是一种不可降解的单价双接头。

Sulfo-SIAB

Sulfo-SIAB Chemical Structure

CAS No. : 106145-13-5

规格 是否有货
1 g 询价
10 g 询价

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生物活性

Sulfo-SIAB is a nonclaevable monovalent bilinker.

IC50 & Target

Non-cleavable

 

分子量

482.20

Formula

C13H11IN2O8S
CAS 号

106145-13-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Gubala V, et al. A comparison of mono and multivalent linkers and their effect on the colloidal stability of nanoparticle and immunoassays performance. Talanta. 2010 Jun 15;81(4-5):1833-9.

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Sulfo-SIAB sodium

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo-SIAB sodium 

Sulfo-SIAB sodium 是一种不可降解的单价双接头。

Sulfo-SIAB sodium

Sulfo-SIAB sodium Chemical Structure

CAS No. : 144650-93-1

规格 是否有货
1 g 询价
10 g 询价

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生物活性

Sulfo-SIAB sodium is a nonclaevable monovalent bilinker.

IC50 & Target

Non-cleavable

 

分子量

504.19

Formula

C13H10IN2NaO8S
CAS 号

144650-93-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Gubala V, et al. A comparison of mono and multivalent linkers and their effect on the colloidal stability of nanoparticle and immunoassays performance. Talanta. 2010 Jun 15;81(4-5):1833-9.

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trans-Sulfo-SMCC

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

trans-Sulfo-SMCC 

trans-Sulfo-SMCC 是一种不可裂解的可透过膜的 ADC 交联剂。

trans-Sulfo-SMCC

trans-Sulfo-SMCC Chemical Structure

CAS No. : 1286837-77-1

规格 价格 是否有货
500 mg ￥27590 询问价格 & 货期

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生物活性

trans-Sulfo-SMCC is a non-cleavable and membrane permeable ADC crosslinker.

IC50 & Target

Non-cleavable

 

分子量

414.39

Formula

C16H18N2O9S
CAS 号

1286837-77-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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Sulfo-SPP

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo-SPP 

Sulfo-SPP 是一种异型双功能交联剂，Sulfo-SPP 的巯基可裂解。

Sulfo-SPP

Sulfo-SPP Chemical Structure

CAS No. : 452072-27-4

规格 价格 是否有货 数量
25 mg 询价
50 mg 询价
100 mg ￥11490 询价
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Sulfo-SPP is a heterobifunctional, thiol-cleavable and membrane impermeable crosslinker.

IC50 & Target

Cleavable

 

分子量

420.48

Formula

C14H16N2O7S3
CAS 号

452072-27-4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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Sulfo-SMPB sodium

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo-SMPB sodium 

Sulfo-SMPB sodium 是一种不可降解 (non-cleavable) 的异双功能化学交联剂，含有 N-羟基丁二酰亚胺 (NHS) 酯和马来酰亚胺基团，允许含胺和巯基的分子共价结合。

Sulfo-SMPB sodium

Sulfo-SMPB sodium Chemical Structure

CAS No. : 92921-26-1

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules[1].

分子量

458.37

Formula

C18H15N2NaO9S
CAS 号

92921-26-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Goldoni S, et al. Biologically active decorin is a monomer in solution. J Biol Chem. 2004 Feb 20;279(8):6606-12.

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SPDB-sulfo

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SPDB-sulfo 

SPDB-sulfo 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

SPDB-sulfo

SPDB-sulfo Chemical Structure

CAS No. : 1628113-16-5

规格 价格 是否有货
100 mg ￥9200 询问价格 & 货期

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生物活性

SPDB-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].

分子量

406.45

Formula

C13H14N2O7S3
CAS 号

1628113-16-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Tinya Abrams, et al. ANTIBODY DRUG CONUGATES. US20140271688A1.

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SPDMV-sulfo

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SPDMV-sulfo 

SPDMV-sulfo 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

SPDMV-sulfo

SPDMV-sulfo Chemical Structure

CAS No. : 2101206-86-2

规格 价格 是否有货
100 mg ￥9200 询问价格 & 货期

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生物活性

SPDMV-sulfo is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs).

分子量

434.51

Formula

C15H18N2O7S3
CAS 号

2101206-86-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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sulfo-SPDB-DM4

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sulfo-SPDB-DM4 

sulfo-SPDB-DM4 是 ADC 的一部分，由 maytansinebased payload (DM4，一种微管抑制剂) 与 sulfo-SPDB 连接而成。

sulfo-SPDB-DM4

sulfo-SPDB-DM4 Chemical Structure

CAS No. : 1626359-59-8

规格 价格 是否有货
1 mg ￥17000 询问价格 & 货期
5 mg ￥51000 询问价格 & 货期
10 mg ￥86000 询问价格 & 货期
25 mg ￥160000 询问价格 & 货期
50 mg ￥250000 询问价格 & 货期

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生物活性

sulfo-SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, an antitubulin agent) via the sulfo-SPDB linker.

IC50 & Target

Maytansinoids

 

体外研究
(In Vitro)

DM4, a structural analogue of maytansine, is a new thiol-containing and potent maytansinoid. DM4 is a cytotoxic maytansinoid drug. It is synthesized in order to link maytansinoids to antibodies via disulfide bonds. Maytansinoids inhibit tubulin polymerization and microtubule assembly and enhance microtubule destabilization, so there is potent suppression of microtubule dynamics resulting in a mitotic block and subsequent apoptotic cell death[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1075.66

Formula

C46H63ClN4O17S3
CAS 号

1626359-59-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.

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DBCO-Sulfo-NHS ester sodium

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

DBCO-Sulfo-NHS ester sodium 

DBCO-Sulfo-NHS ester sodium 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。

DBCO-Sulfo-NHS ester sodium

DBCO-Sulfo-NHS ester sodium Chemical Structure

CAS No. : 1400191-52-7

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

532.50

Formula

C25H21N2NaO8S
CAS 号

1400191-52-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Jung S, et al. Facile strategy for protein conjugation with chitosan-poly(ethylene glycol) hybrid microparticleplatforms via strain-promoted alkyne-azide cycloaddition (SPAAC) reaction. Biomacromolecules. 2013 Nov 11;14(11):3892-902.

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DBCO-Sulfo-Link-biotin

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

DBCO-Sulfo-Link-biotin 

DBCO-Sulfo-Link-biotin 是一种可降解 (cleavable) 的 ADC linker，用于抗体偶联药物 (ADCs) 的合成。

DBCO-Sulfo-Link-biotin

DBCO-Sulfo-Link-biotin Chemical Structure

CAS No. : 1363444-70-5

规格 是否有货
1 mg 询价

* Please select Quantity before adding items.

生物活性

DBCO-Sulfo-Link-biotin is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target[1]

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

653.77

Formula

C31H35N5O7S2
CAS 号

1363444-70-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Portnoff AD, et al. An antidote approach to reduce risk and broaden utility of antibody-based therapeutics. J Biol Chem. 2017 May 19;292(20):8498-8506.

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Sulfo DBCO-amine

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo DBCO-amine 

Sulfo DBCO-amine 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

Sulfo DBCO-amine

Sulfo DBCO-amine Chemical Structure

CAS No. : 2028284-70-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Sulfo DBCO-amine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

427.47

Formula

C21H21N3O5S
CAS 号

2028284-70-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Sulfo DBCO-PEG4-amine

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo DBCO-PEG4-amine 

Sulfo DBCO-PEG4-amine 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Sulfo DBCO-PEG4-amine

Sulfo DBCO-PEG4-amine Chemical Structure

CAS No. : 2055198-05-3

规格 价格 是否有货
50 mg ￥7400 询问价格 & 货期
100 mg ￥12550 询问价格 & 货期

* Please select Quantity before adding items.

生物活性

Sulfo DBCO-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

678.79

Formula

C32H46N4O10S
CAS 号

2055198-05-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Sulfo DBCO-PEG4-Maleimide

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo DBCO-PEG4-Maleimide 

Sulfo DBCO-PEG4-Maleimide 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Sulfo DBCO-PEG4-Maleimide

Sulfo DBCO-PEG4-Maleimide Chemical Structure

CAS No. : 2055198-07-5

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

825.88

Formula

C39H47N5O13S
CAS 号

2055198-07-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Sulfo-NHS-Acetate

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo-NHS-Acetate 

Sulfo-NHS-Acetate 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

Sulfo-NHS-Acetate

Sulfo-NHS-Acetate Chemical Structure

CAS No. : 152305-87-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

237.19

Formula

C6H7NO7S
CAS 号

152305-87-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Sulfo-NHS-Acetate

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Sulfo-NHS-Acetate 

Sulfo-NHS-Acetate 是一种 PROTAC linker，属于 alkyl chain 类。可用于合成 PROTAC 分子。

Sulfo-NHS-Acetate

Sulfo-NHS-Acetate Chemical Structure

CAS No. : 152305-87-8

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

237.19

Formula

C6H7NO7S
CAS 号

152305-87-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Methyltetrazine-Sulfo-NHS ester sodium

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Methyltetrazine-Sulfo-NHS ester sodium 

Methyltetrazine-Sulfo-NHS ester (sodium) 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子。

Methyltetrazine-Sulfo-NHS ester sodium

Methyltetrazine-Sulfo-NHS ester sodium Chemical Structure

CAS No. : 1821017-46-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

429.34

Formula

C15H12N5NaO7S
CAS 号

1821017-46-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Methyltetrazine-Sulfo-NHS ester sodium

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Methyltetrazine-Sulfo-NHS ester sodium 

Methyltetrazine-Sulfo-NHS ester (sodium) 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子。

Methyltetrazine-Sulfo-NHS ester sodium

Methyltetrazine-Sulfo-NHS ester sodium Chemical Structure

CAS No. : 1821017-46-2

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

429.34

Formula

C15H12N5NaO7S
CAS 号

1821017-46-2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务