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mPEG hydrazide
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- SDS
- DataSheet
标签归档：cat
7-diethylaminocoumarin NHS Cat. No. CM-NS-02 ex/em: 409/473 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
7-diethylaminocoumarin NHS
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mPEG hydrazide Cat. No. PG1-HZ-10k 10000 Da 250 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
mPEG hydrazide
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- SDS
- DataSheet
mPEG hydrazide Cat. No. PG1-HZ-20k 20000 Da 250 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
mPEG hydrazide
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- SDS
- DataSheet
mPEG hydrazide Cat. No. PG1-HZ-30k 30000 Da 250 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
mPEG hydrazide
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- SDS
- DataSheet
Hydrazide PEG Hydrazide Cat. No. PG2-HZ-5k 5000 Da 500 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Hydrazide PEG Hydrazide
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- SDS
- DataSheet
Hydrazide PEG Hydrazide Cat. No. PG2-HZ-3k 3400 Da 500 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Hydrazide PEG Hydrazide
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- SDS
- DataSheet
Hydrazide PEG Hydrazide Cat. No. PG2-HZ-2k 2000 Da 500 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Hydrazide PEG Hydrazide
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- SDS
- DataSheet
Cholesterol succinate Cat. No. CSL01 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cholesterol succinate
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Cholesterol NHS Cat. No. CSL02 25 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Cholesterol NHS
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6-maleimidocaproic acid Cat. No. M-6C-1 100 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
6-maleimidocaproic acid
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Description:
Nanocs SnapLink maleimide acid is an amine and sulfhydryl reactive crosslinker. This crossliker is non-cleavable and water soluble. It contains a carboxylic acid that can be activated with EDC and reacts toward primary amine groups. The maleimide group reacts with available sulfhydryl groups from naturally occurring or mutagenically derived cysteine residues at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Appearance: Off-white/white solid;
- Purity: >95%
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Disuccinimidyl sebacate Cat. No. DS2-102 250 mg修饰性聚乙二醇
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Disuccinimidyl sebacate
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Bifunctional amine reactive NHS molecule
2-Maleimidoethyl amine Cat. No. M-C2A-1 CAS# 146474-00-2 5 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
2-Maleimidoethyl amine
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Description:
Nanocs SnapLink maleimide amine is a heterobifunctional crosslinker. This crosslinker contains a primary amine group that can be reacted with a variety of amine reactive groups, such as NHS. The maleimide group reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Appearance: Off-white/white solid;
- Purity: >95%
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Maleimidopropionic hydrazide Cat. No. M-C3HZ-1 10 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimidopropionic hydrazide
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Description:
Nanocs SnapLink maleimide hydrazide is a heterobifunctional crosslinker. This crosslinker contains a hydrazide group that can be reacted with carbohydrate. The maleimide group reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Appearance: Off-white/white solid;
- Purity: >95%
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
Maleimidocaproic hydrazide Cat. No. M-C6HZ-1 10 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
Maleimidocaproic hydrazide
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Description:
Nanocs SnapLink maleimide hydrazide is a heterobifunctional crosslinker. This crosslinker contains a hydrazide group that can be reacted with carbohydrate. The maleimide group reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds.
Physical Properties:
- Appearance: Off-white/white solid;
- Purity: >95%
Storage Conditions:
- Store at -20 0C, dessiccated. Avoid frequent thaw and freeze.
N-ethylmaleimide, NEM Cat. No. M-C2-1 CAS# 128-53-0 1 g修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
N-ethylmaleimide, NEM
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Description:
N-ethylmaleimide (NEM) is a water soluble, thiol reactive maleimide that can be used to modify protein cysteine residues. Maleimide reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds. NEM has been used for protein Acyl-RAC assay. N-ethylmaleimide is a sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 µM) in pancreatic duct cells. N-ethylmaleimide Inactivates NADP-dependent isocitrate dehydrogenase. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei. NEM stimulates arachidonic acid release through activation of PLA2 in endothelial cells. As a commonly used sulfhydryl alkylating reagent, NEM has been used for blocking sulfhydryl containing reagents which interfere with glucose oxidase assays. Inactivates NADP-dependent isocitrate dehydrogenase. Endonuclease inhibitor. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei.
Physical Properties:
- Appearance: Off-white/faint yellow solid
- Mol Wt: 125.13
- CAS No: 128-53-0
- Purity: >98%
Storage Conditions:
- Store at -20 0C.
| AR-SS-1 , Agarose, S3 high capacity acyl-RAC capture beads |
| AR-SR-1 , Thiol reducing Agarose beads |
N-ethylmaleimide, NEM Cat. No. M-C2-2 CAS# 128-53-0 5 g修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
N-ethylmaleimide, NEM
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Description:
N-ethylmaleimide (NEM) is a water soluble, thiol reactive maleimide that can be used to modify protein cysteineresidues. Maleimide reacts with sulfhydryl groups at pH 6.5~7.5 to form stable thioether bonds. NEM has been used for protein Acyl-RAC assay. N-ethylmaleimide is a sulfhydryl alkylating reagent that inhibits H+-ATPase and suppresses the short circuit current (IC50 = 22 µM) in pancreatic duct cells. N-ethylmaleimide Inactivates NADP-dependent isocitrate dehydrogenase. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei. NEM stimulates arachidonic acid release through activation of PLA2 in endothelial cells. As a commonly used sulfhydryl alkylating reagent, NEM has been used for blocking sulfhydryl containing reagents which interfere with glucose oxidase assays. Inactivates NADP-dependent isocitrate dehydrogenase. Endonuclease inhibitor. Also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei.
Physical Properties:
- Appearance: Off-white/faint yellow solid
- Mol Wt: 125.13
- CAS No: 128-53-0
- Purity: >98%
Storage Conditions:
- Store at -20 0C.
| AR-NTA-1 , Ni-NTA His-select Agarose Beads |
| AR-SS-1 , Agarose, S3 high capacity acyl-RAC capture beads |
| AR-SR-1 , Thiol reducing Agarose beads |
mPEG propionaldehyde Cat. No. PG1-ALP-5k 5000 Da 250 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
mPEG propionaldehyde
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Methoxy PEG propionaldehyde is a stable aldehyde PEG that can be used for protein, antibody, peptides or carbohydrate N-terminal amine group pegylation reagent. The reaction between aldehyde group with the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with n-terminus amine groups at a pH of from 5.0 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups.
Physical Properties:
- Off-white/white solid;
- Soluble in water, DMSO, DMF;
- Activity >90%; Peroxide<10ppm;
Storage Conditions:
- Store at -20 0C
Reaction Procedures:
Generally, a 5- to 10-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer: Amine-free aqueous buffer, pH 5.0~6.5.
- PEG aldehyde stock solution: 50 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
mPEG propionaldehyde Cat. No. PG1-ALP-2k 2000 Da 250 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
mPEG propionaldehyde
|
Methoxy PEG propionaldehyde is a stable aldehyde PEG that can be used for protein, antibody, peptides or carbohydrate N-terminal amine group pegylation reagent. The reaction between aldehyde group with the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with n-terminus amine groups at a pH of from 5.0 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups.
Physical Properties:
- Off-white/white solid;
- Soluble in water, DMSO, DMF;
- Activity >90%; Peroxide<10ppm;
Storage Conditions:
- Store at -20 0C
Reaction Procedures:
Generally, a 5- to 10-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer: Amine-free aqueous buffer, pH 5.0~6.5.
- PEG aldehyde stock solution: 50 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet
mPEG propionaldehyde Cat. No. PG1-ALP-10k 10000 Da 250 mg修饰性聚乙二醇
上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。
mPEG propionaldehyde
|
Methoxy PEG propionaldehyde is a stable aldehyde PEG that can be used for protein, antibody, peptides or carbohydrate N-terminal amine group pegylation reagent. The reaction between aldehyde group with the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with n-terminus amine groups at a pH of from 5.0 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups.
Physical Properties:
- Off-white/white solid;
- Soluble in water, DMSO, DMF;
- Activity >90%; Peroxide<10ppm;
Storage Conditions:
- Store at -20 0C
Reaction Procedures:
Generally, a 5- to 10-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.
Materials Required:
- Pegylation buffer: Amine-free aqueous buffer, pH 5.0~6.5.
- PEG aldehyde stock solution: 50 mg in 1 mL conjugation buffer.
- Washing solution: Distilled water or any aqueous buffer.
Reaction Steps:
Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.
- SDS
- DataSheet