标签归档：steroid

多肽定制Steroid Receptor Coactivator-1 (682-697) 编码

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名称 Steroid Receptor Coactivator-1 (682-697)
编码
别名 Steroid Receptor Coactivator-1 (682-697)
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） SLTARHKILHRLLQEG
序列（三字母缩写） Ser-Leu-Thr-Ala-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly
基本描述
溶解度
分子量 1872.22
化学式 C82H142N28O22
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Steroid Receptor Coactivator-1 (682-697) 编码
Figures Steroid Receptor Coactivator-1 (682-697) 编码
Reference
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多肽定制Steroid Receptor Coactivator-1 (SRC-1), (6 编码

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上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Steroid Receptor Coactivator-1 (SRC-1), (6
编码
别名 Steroid Receptor Coactivator-1 (SRC-1), (6
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） Biotin-CPSSHSSLTERHKILHRLLQEGSPS
序列（三字母缩写） Biotin-Cys-Pro-Ser-Ser-His-Ser-Ser-Leu-Thr-Glu-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-Gly-Ser-Pro-Ser-OH (trifluoroacetate salt)
基本描述 TET 830 modified/T-helper epitope from tetanus toxoid is a universal human tetanus toxin T cell epitope. It induces T-cell activation and is used as a helper peptide in vaccinations.
溶解度
分子量 3026.42
化学式 C128H209N41O40S2
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Steroid Receptor Coactivator-1 (SRC-1), (6 编码
Figures Steroid Receptor Coactivator-1 (SRC-1), (6 编码
Reference
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多肽定制Steroid Receptor Co-Factor Peptide 编码

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上海金畔生物科技有限公司可以定制不同序列多肽，可以访问官网了解更多产品信息。

名称 Steroid Receptor Co-Factor Peptide
编码
别名 Steroid Receptor Co-Factor Peptide
纯度 80%，90%，95%，98%，99%
重量 1mg,5mg,10mg,50mg,100mg,1g
序列（单字母缩写） LTERHKILHRLLQE
序列（三字母缩写） H-Leu-Thr-Glu-Arg-His-Lys-Ile-Leu-His-Arg-Leu-Leu-Gln-Glu-OH (trifluoroacetate salt)
基本描述 This is amino acids 676 to 700 fragment of steroid receptor co-activator (SRC1). This N-terminnaly biotinylated peptide is derived from the second LXXLL motif of SRC1. Co-activator proteins interact with nuclear receptors in a ligand-dependent manner and augment transcription. A short amphipathic betalpha-Helical domain that includes this LXXLL motif serves as the interaction interface between the co-activator molecules and the ligand-dependent activation function (AF-2) located in the COOH-terminus of the nuclear receptor ligand-binding domain (LBD). Receptor binding domain of the co-activator SRC-1 is specifically recruited to the farnesoid X receptor (FXR) ligand-binding domain
溶解度
分子量 1786.1
化学式 C79H136N26O21
存储条件 Store at -20°C. Keep tightly closed. Store in a cool dry place.
注释
Documents Steroid Receptor Co-Factor Peptide 编码
Figures Steroid Receptor Co-Factor Peptide 编码
Reference Bramlett, K. et al. Mol. Endocrinol. 15, 909 (2001)
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Steroid sulfatase-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Steroid sulfatase-IN-1 

Steroid sulfatase-IN-1 是一种有效的且具有口服活性的 Steroid sulfatase 抑制剂，IC50 为 1.71 µM。Steroid sulfatase-IN-1 在体内发挥抗肿瘤作用 (TGI=51%)。Steroid sulfatase-IN-1 具有乳腺癌研究潜力。

Steroid sulfatase-IN-1

Steroid sulfatase-IN-1 Chemical Structure

CAS No. : 2403716-19-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 µM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer[1].

IC50 & Target

IC50: 1.71 µM (Steroid sulfatase)[1]
体内研究
(In Vivo)

Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51%[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 67NR mouse[1]
Dosage: 50 mg/kg
Administration: P.o.
Result: Showed significant antitumor activity with the TGI value of 51%.

分子量

385.23

Formula

C14H10Cl2N4O3S
CAS 号

2403716-19-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Biernacki K, et al. Development of Sulfamoylated 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer. J Med Chem. 2022; 65(6):5044-5056.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Steroid sulfatase-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Steroid sulfatase-IN-1 

Steroid sulfatase-IN-1 是一种有效的且具有口服活性的 Steroid sulfatase 抑制剂，IC50 为 1.71 µM。Steroid sulfatase-IN-1 在体内发挥抗肿瘤作用 (TGI=51%)。Steroid sulfatase-IN-1 具有乳腺癌研究潜力。

Steroid sulfatase-IN-1

Steroid sulfatase-IN-1 Chemical Structure

CAS No. : 2403716-19-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 µM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer[1].

IC50 & Target

IC50: 1.71 µM (Steroid sulfatase)[1]
体内研究
(In Vivo)

Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51%[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 67NR mouse[1]
Dosage: 50 mg/kg
Administration: P.o.
Result: Showed significant antitumor activity with the TGI value of 51%.

分子量

385.23

Formula

C14H10Cl2N4O3S
CAS 号

2403716-19-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Biernacki K, et al. Development of Sulfamoylated 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer. J Med Chem. 2022; 65(6):5044-5056.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Steroid sulfatase-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Steroid sulfatase-IN-1 

Steroid sulfatase-IN-1 是一种有效的且具有口服活性的 Steroid sulfatase 抑制剂，IC50 为 1.71 µM。Steroid sulfatase-IN-1 在体内发挥抗肿瘤作用 (TGI=51%)。Steroid sulfatase-IN-1 具有乳腺癌研究潜力。

Steroid sulfatase-IN-1

Steroid sulfatase-IN-1 Chemical Structure

CAS No. : 2403716-19-6

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Steroid sulfatase-IN-1 is a potent and orally active Steroid sulfatase inhibitor with an IC50 of 1.71 µM. Steroid sulfatase-IN-1 shows antitumor activity (TGI=51%) in vivo. Steroid sulfatase-IN-1 has the potential for the research of breast cancer[1].

IC50 & Target

IC50: 1.71 µM (Steroid sulfatase)[1]
体内研究
(In Vivo)

Steroid sulfatase-IN-1 (compound 4 b) (50 mg/kg; p.o.) shows significant antitumor activity with the TGI value of 51%[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 67NR mouse[1]
Dosage: 50 mg/kg
Administration: P.o.
Result: Showed significant antitumor activity with the TGI value of 51%.

分子量

385.23

Formula

C14H10Cl2N4O3S
CAS 号

2403716-19-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Biernacki K, et al. Development of Sulfamoylated 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)phenol Derivatives as Potent Steroid Sulfatase Inhibitors for Efficient Treatment of Breast Cancer. J Med Chem. 2022; 65(6):5044-5056.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务