Dimethylamine-d6 hydrochloride

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-d6 hydrochloride  纯度: ≥99.0%

Dimethylamine-d6 hydrochloride 是一种氘代标记的 Dimethylamine hydrochloride。Dimethylamine hydrochloride 是二甲基亚硝胺的直接前体,二甲基亚硝胺是一种已知的多种动物体内的强效致癌物。

Dimethylamine-d6 hydrochloride

Dimethylamine-d6 hydrochloride Chemical Structure

CAS No. : 53170-19-7

规格 价格 是否有货 数量
25 mg ¥500 In-stock
50 mg ¥800 In-stock
100 mg ¥1300 In-stock
200 mg   询价  
500 mg   询价  

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生物活性

Dimethylamine-d6 hydrochloride is a deuterium labeled Dimethylamine hydrochloride. Dimethylamine hydrochloride is the immediate precursor of dimethylnitrosamine, a known potent carcinogen in a wide variety of animal species[1].

分子量

87.58

Formula

C2H2D6ClN

CAS 号

53170-19-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Zhang AQ, et al. Dimethylamine formation in the rat from various related amine precursors. Food Chem Toxicol. 1998;36(11):923-927.

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Dimethylamine-SPDB

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-SPDB 

Dimethylamine-SPDB 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。

Dimethylamine-SPDB

Dimethylamine-SPDB Chemical Structure

CAS No. : 1193111-73-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

分子量

369.46

Formula

C15H19N3O4S2

CAS 号

1193111-73-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Dimethylamine-SPDB

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-SPDB 

Dimethylamine-SPDB 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。

Dimethylamine-SPDB

Dimethylamine-SPDB Chemical Structure

CAS No. : 1193111-73-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

分子量

369.46

Formula

C15H19N3O4S2

CAS 号

1193111-73-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Dimethylamine-SPDB

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-SPDB 

Dimethylamine-SPDB 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。

Dimethylamine-SPDB

Dimethylamine-SPDB Chemical Structure

CAS No. : 1193111-73-7

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

分子量

369.46

Formula

C15H19N3O4S2

CAS 号

1193111-73-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Dimethylamine-PEG19

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-PEG19 

Dimethylamine-PEG19 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Dimethylamine-PEG19

Dimethylamine-PEG19 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

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生物活性

Dimethylamine-PEG19 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

926.13

Formula

C42H87NO20

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Dimethylamine-PEG19

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-PEG19 

Dimethylamine-PEG19 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Dimethylamine-PEG19

Dimethylamine-PEG19 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Dimethylamine-PEG19 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

926.13

Formula

C42H87NO20

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Dimethylamine-PEG19

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Dimethylamine-PEG19 

Dimethylamine-PEG19 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

Dimethylamine-PEG19

Dimethylamine-PEG19 Chemical Structure

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Dimethylamine-PEG19 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

926.13

Formula

C42H87NO20

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务