Megazyme生物及食品酶法检测试剂盒 E-BGLAEC -Glucuronidase (E.coli) 3402
日度归档:2023年10月24日
器具和容器包装试验用|食品分析用试剂|理化学分析产品|食品|关东化学株式会社
挥发性物质混合标准液Ⅱ(5种)+内部标准的分析例
■产品微波炉
酸类分析例
■产品微波炉
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医药/化妆品(新信息事业绍介)|关东化学株式会社
事业绍介
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Megazyme生物及食品酶法检测试剂盒 O-XCBIR Xylosyl Cellobiose (reduced) 50mg
Megazyme生物及食品酶法检测试剂盒 O-XCBIR Xylosyl Cellobiose (reduced) 50mg 2664
Nifedipine(Synonyms: 硝苯地平; BAY-a-1040)
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Nifedipine (Synonyms: 硝苯地平; BAY-a-1040) 纯度: 99.35%
Nifedipine (BAY-a-1040) 是有效的钙离子通道 (calcium channel) 阻滞剂,常用于心肌功能不全的相关研究。
Nifedipine Chemical Structure
CAS No. : 21829-25-4
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生物活性 |
Nifedipine (BAY-a-1040) is a potent calcium channel blocker and drug of choice for cardiac insufficiencies. |
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体外研究 (In Vitro) |
Nifedipine (BAY-a-1040) (100 μM) significantly lowers the viability of the WKPT-0293 Cl.2 Cells, and treatment of nifedipine (10 or 100 μM) plus FAC induces a significant reduction in cell viability, but there are no significant differences in viability between the control cells and the cells treated with 100 μM of FAC or 1 and 10 μM of nifedipine.Nifedipine (BAY-a-1040) (1, 10, or 100 μM) significantly increases iron level in WKPT-0293 Cl.2 cells. Nifedipine treatment also increases expression of TfR1, DMT1+IRE and DMT1-IRE in WKPT-0293 Cl.2 cells. In addition, co-treatment with nifedipine (100 μM) and FAC (100 μM) increases TfR1, DMT1+IRE and DMT1-IRE expression in WKPT-0293 Cl.2 cells[2]. Nifedipine plus ritodrine produces a significantly greater inhibition of contractility than each drug alone in the midrange of concentrations. The combination of nifedipine plus nitroglycerin or nifedipine plus atosiban produces a significantly greater inhibition than nitroglycerin or atosiban alone but not greater than nifedipine. The combination of nifedipine plus NS-1619 (Ca2+-activated K+ [BKCa] channel opener) reduces the inhibitory effect of each drug[3]. Nifedipine (BAY-a-1040) (2 μM) significantly inhibits P. capsici mycelial growth and sporulation. Nifedipine (BAY-a-1040)-induced inhibition of mycelial growth is calcium-dependent. Nifedipine (0.5 μM) increases P. capsici sensitivity to H2O2 in a calcium-dependent manner. Nifedipine inhibition of P. capsici virulence and expression of genes involved in pathogenicity[4]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
In Nifedipine (BAY-a-1040) (50 mg/kg)- and CsA-treated rats, the BL dimensions (BLi and BLk), MD dimensions (MDk) and vertical dimensions (VHi and VHk) are significantly increased (P < 0.05) at the end of the 4th week[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
346.33 |
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Formula |
C17H18N2O6 |
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CAS 号 |
21829-25-4 |
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中文名称 |
硝苯地平;心痛定;硝苯吡啶;硝苯啶 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (288.74 mM; Need ultrasonic) H2O : 1 mg/mL (2.89 mM; ultrasonic and warming and heat to 80°C) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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Cell Assay [2] |
Cell viability is assessed using an MTT assay. Briefly, a total of 25 μL MTT (1 g/L in PBS) is added to each well before incubation is conducted at 37°C for 4 h. The assay is stopped by the addition of a 100 μL lysis buffer (20% SDS in 50% N’Ndimethylformamide, pH 4.7). Optical density (OD) is measured at the 570 nm wavelength by the use of an ELX-800 microplate assay reader and the results are expressed as a percentage of the absorbance measured in the control cells. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Animal Administration [1] |
All the 30 rats are randomLy distributed into three equal groups of ten animals each. Group 1 (control) receive olive oil for the 8 weeks. Group 2 and Group 3 receive a combination of CsA (30 mg/kg body weight) and Nf (50 mg/kg body weight) in olive oil for 8 weeks. In Group 3 rats, Azi (10 mg/kg body weight) is added to this regimen, in the 5th week. The total study period is 8 weeks. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
参考文献 |
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英国Techne全尺寸基因扩增仪5PrimeG/05(60×0.5ml)
【简单介绍】
【详细说明】
Megazyme生物及食品酶法检测试剂盒 K-AGLUA Alpha-Glucuronidase
Megazyme生物及食品酶法检测试剂盒 K-AGLUA Alpha-Glucuronidase 3600
Megazyme生物及食品酶法检测试剂盒 C-CLFR-5G Calcofluor Fluorescent Stain
Megazyme生物及食品酶法检测试剂盒 C-CLFR-5G Calcofluor Fluorescent Stain 1782
二氢石蒜碱对照品
【编号】:PR0496
【产品名称】:二氢石蒜碱对照品
【规格】:10mg
【用途】:
二氢石蒜碱对照品
Megazyme生物及食品酶法检测试剂盒 E-MALTS Alpha-Glucosidase (Maltase)
Megazyme生物及食品酶法检测试剂盒 E-MALTS Alpha-Glucosidase (Maltase) 2682
Biotin-PEG12-NHS ester
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Biotin-PEG12-NHS ester 纯度: ≥98.0%
Biotin-PEG12-NHS ester 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
Biotin-PEG12-NHS ester Chemical Structure
CAS No. : 1934296-88-4
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
50 mg | ¥7800 | In-stock | |
100 mg | 询价 | ||
200 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
Biotin-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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IC50 & Target |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
941.09 |
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Formula |
C41H72N4O18S |
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CAS 号 |
1934296-88-4 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (106.26 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
*以上所有助溶剂都可在 Shanghai Jinpan Biotech Co Ltd 网站选购。
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参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
Allantoin(Synonyms: 尿囊素; 5-Ureidohydantoin)
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Allantoin (Synonyms: 尿囊素; 5-Ureidohydantoin) 纯度: 99.85%
Allantoin是促进皮肤健康,刺激新鲜健康组织生长的皮肤调理剂。
Allantoin Chemical Structure
CAS No. : 97-59-6
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥550 | In-stock | |
100 mg | ¥500 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
Allantoin 相关产品
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- Inactive Ingredient Library
- Targeted Diversity Library
- Rare Diseases Drug Library
生物活性 |
Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. |
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IC50 & Target |
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体外研究 (In Vitro) |
Allantoin is a well-known cosmetic ingredient reported to have anti-oxidative and anti-inflammatory activities[1]. Allantoin attenuates apoptosis and cytotoxicity and increased the viability of STZ-induced β-cells in a dose-dependent manner. Allantoin decreases the level of caspase-3 and increases the level of phosphorylated B-cell lymphoma 2 (Bcl-2) expression. Allantoin has been demonstrated to activate imidazoline 3 (I3) receptors[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
The subchronic administration of allantoin (1, 3 or 10 mg/kg, for 7 days) significantly increases the latency time measured during the passive avoidance task in scopolamine-induced cholinergic blockade and normal naive mice. Allantoin treatment (3 or 10 mg/kg, for 7 days) also increases the expression levels of phosphorylated phosphatidylinositide 3-kinase (PI3K), phosphorylated protein kinase B (Akt) and phosphorylated glycogen synthase kinase-3β (GSK-3β). Allantoin significantly increases the neuronal cell proliferation of immature neurons in the hippocampal dentate gyrus region[1]. Daily injection of allantoin for 8 days in STZ-treated rats significantly lowers plasma glucose and increases plasma insulin levels [2]. Allantoin decreases blood pressures in SHRs at 30 minutes, as the most effective time. Also, this antihypertensive action is shown in a dose-dependent manner from SHRs treated with allantoin. Moreover, in anesthetized rats, allantoin inhibits cardiac contractility and heart rate. Also, the peripheral blood flow is markedly increased by allantoin[3]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Clinical Trial |
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分子量 |
158.12 |
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Formula |
C4H6N4O3 |
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CAS 号 |
97-59-6 |
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中文名称 |
尿囊素 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (316.22 mM; Need ultrasonic) H2O : 3.85 mg/mL (24.35 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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Cell Assay [2] |
Pancreatic β-cells are treated with 1, 10, 100 μM of allantoin before 30 min prior to the addition of 5 mM STZ and incubated for 6 h. Cell viability is measured using the ApoTox-Glo triplex assay[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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Animal Administration [1][3] |
Rats: Animals are randomly assigned into four groups: (I) the control group treated with the vehicle, saline; (II) the allantoin group treated by intravenous injection of allantoin at 0.5 mg/kg; (III) the allantoin+efaroxan group treated with allantoin at the most effective dose (0.5 mg/kg, i.v.) and efaroxan at effective dose (1.5 mg/kg, i.v.) 30 minutes before injection of allantoin; and (IV) the allantoin treated SHRs group treated by intravenous injection of allantoin at various dose for desired time. After treatment of allantoin, the rats are placed into a holder for the determination of the mean blood pressure[3]. Mice: For memory ameliorating study, mice are administered vehicle solution, allantoin (1, 3 or 10 mg/kg, p.o.) or donepezil (5 mg/kg, p.o.) at the same time (10:00-12:00 a.m) and same place for 7 days. For memory enhancing study, mice are administered vehicle solution, allantoin (1, 3 or 10 mg/kg, p.o.) or piracetam (200 mg/kg, i.p.). The final administration of allantoin, donepezil or piracetam is performed 1 h before an acquisition trial in the passive avoidance task[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
参考文献 |
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所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务
Megazyme生物及食品酶法检测试剂盒 E-BGOSPC -Glucosidase (P. chrysosporium)
Megazyme生物及食品酶法检测试剂盒 E-BGOSPC -Glucosidase (P. chrysosporium) 2844
12根用贴纸固定螺丝PEEK 2个|柴田科技有限公司-环境检测设备、科学仪器的制造销售
产品详细
12根用贴纸固定螺丝PEEK 2个
商品代码其他情报(式样)
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上海金畔生物科技有限公司
” 753%2F%3Fc%3D35 “> 753%2F%3Fc%3D35
经上皮电阻(TEER)测定装置|经上皮电阻(TEER)测定装置|生化学相关设备|试剂|关东化学株式会社
专用电极而稳定的测量
电脑显示数据保存·解析对应
温度传感器的温度测量对应
TEER值测量一边插入内的访问量可能
眼睛刺激性试验法“Vitrigel®- EIT法」对应
使用方法
特征
专用电极而稳定的测量
电脑显示数据保存·解析对应
温度传感器的温度测量对应
TEER值测量一边插入内的访问量可能
眼睛刺激性试验法“Vitrigel®- EIT法」对应
产品信息
小册子(PDF)
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Megazyme生物及食品酶法检测试剂盒 E-GPDHEC Glucose 6-phosphate dehydrogenase
Megazyme生物及食品酶法检测试剂盒 E-GPDHEC Glucose 6-phosphate dehydrogenase 2592
FT671
上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
FT671 纯度: 99.79%
FT671是有效、非共价的、选择性的 USP7 抑制剂,IC50 值为 52 nM,与USP7催化域结合的 Kd 值为65 nM。
FT671 Chemical Structure
CAS No. : 1959551-26-8
规格 | 价格 | 是否有货 | 数量 |
---|---|---|---|
Free Sample (0.1-0.5 mg) | Apply now | ||
10 mM * 1 mL in DMSO | ¥3345 | In-stock | |
1 mg | ¥1400 | In-stock | |
5 mg | ¥2850 | In-stock | |
10 mg | ¥5250 | In-stock | |
25 mg | ¥11250 | In-stock | |
50 mg | ¥18750 | In-stock | |
100 mg | ¥29250 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
* Please select Quantity before adding items.
FT671 相关产品
•相关化合物库:
- Covalent Screening Library Plus
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- Anti-Blood Cancer Compound Library
生物活性 |
FT671 is a potent, non-covalent and selective USP7 inhibitor with an IC50 of 52 nM and binds to the USP7 catalytic domain with a Kd of 65 nM. |
IC50 & Target |
IC50: 52 nM (USP7)[1] Kd: 65 nM (USP7)[1] |
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体外研究 (In Vitro) |
FT671 increases p53 protein levels in HCT116 or bone osteosarcoma (U2OS) cell lines, leading to induction of p53 target genes including BBC3 (which encodes PUMA), CDKN1A (p21), RPS27L (S27L) and MDM2. FT671 leads to the degradation of N-Myc and upregulation of p53 in the neuroblastoma cell line IMR-32. FT671 also stabilizes p53 in the MM.1S multiple myeloma cell line, which correlates with increased MDM2 ubiquitination and leads to expression of p53 target genes[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
FT671 (100 mg/kg and 200 mg/kg, Oral gavage, daily) treatment in mice leads to a significant dose-dependent inhibition of tumor growth. And FT671 is well-torelated even at high doses[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
533.48 |
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Formula |
C24H23F4N7O3 |
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CAS 号 |
1959551-26-8 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
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溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (93.72 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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抗βIII-微管蛋白抗体[ ep1331y ] – Microtubule Marker(ab52901)
种属反应性
靶标
功能 微管蛋白是微管的主要成分。 它与两摩尔的GTP,一对β链交换场地,在α链的非交换性网站。 在适当TUBB3轴突导向和维护关键作用。 组织特异性 表达主要局限于中枢和外周神经系统。 疾病相关 缺陷在TUBB3是先天性眼外肌3A型纤维化的原因(cfeom3a)[ 600638 ] MIM。 先天性眼球运动障碍,以限制性眼肌麻痹的眼外肌的神经支配由动眼神经和滑车神经。 其临床特征为锚的眼睛向下凝视,上睑下垂,向后倾斜的头部。 先天性眼外肌纤维化3型表现为非进行性,常染色体显性遗传疾病变量表达式。 患者可能是单侧或双侧,影响,和他们的眼运动缺陷范围从完全性眼肌麻痹(用眼睛固定在一次和外斜视的位置),轻度无症状限制眼球运动。 上睑下垂,屈光不正,弱视,代偿头位的障碍,更严重的形式相关。 在某些情况下,眼部表型是伴随着额外的功能,包括发育延迟、胼胝体、基底节的畸形,面部无力,多发性神经病。 序列相似性 属于微管蛋白家族。 结构域 高酸性的C-端区域可结合阳离子如钙。 翻译后修饰 在C-末端谷氨酸残基的一些polyglutamylated。 这种修改只发生在谷氨酸残基,结果在γ-羧基谷氨酸链。 也monoglycylated但不polyglycylated由于在人体功能ttll10缺席。 monoglycylation主要限于并入axonemes微管蛋白(纤毛和鞭毛)而在神经元细胞,glutamylation盛行的中心粒,axonemes,和有丝分裂纺锤体。 无论是修改可以对相邻残基相同的蛋白共存,并降低glycylation水平增加polyglutamylation,往复。 这样的修改的确切功能尚不清楚但他们调节轴丝微管的装配和动态。 细胞定位 细胞质骨架>。 -
英国Techne Prime全尺寸基因扩增仪5Prime/384(384孔板)
【简单介绍】
【详细说明】
二氢醉椒素对照品
【编号】:PR0495
【产品名称】:二氢醉椒素对照品
【规格】:10mg
【用途】:
二氢醉椒素对照品
编号:PR0495英文名称:Dihydrokawain英文别名:MarindininCas 号: 587-63-3分 子 式:C14H16O3分 子 量:232.279植物来源:卡瓦胡椒来源: Root of Piper methysticum and Aniba gigantifolia纯度: 95%~99%分析方法: HPLC-DAD or/and HPLC-ELSD鉴定方法: 质谱(Mass), 核磁(NMR)包装: 棕色小玻璃瓶,标准包装10mg,20mg,50mg;可以按客户需求包装。类别:上海金畔生物科技有限公司,天然提取物作为标准品,对照品或者供研究用,不能直接用于人体。